{"id":"W4392048822","doi":"10.1038/s41598-024-54676-8","title":"Repeated microdoses of LSD do not alter anxiety or boldness in zebrafish","year":2024,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Zebrafish Biomedical Research Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"MacEwan University; Women and Children’s Health Research Institute; University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada; University of Alberta","keywords":"Boldness; Zebrafish; Danio; Anxiety; Animal model; Physiology; Psychology; Biology; Medicine; Internal medicine; Psychiatry; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001412581,0.0001146889,0.0001459009,0.0001784151,0.00006411873,0.000166525,0.0002218404,0.0001293084,0.000195822],"category_scores_gemma":[0.0006431424,0.00008939011,0.00009156086,0.000866433,0.0004578993,0.000009557009,0.0002034351,0.000122351,0.00001864958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002504523,"about_ca_system_score_gemma":0.0004759199,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003878413,"about_ca_topic_score_gemma":0.00008763068,"domain_scores_codex":[0.9978396,0.00004762063,0.0004921339,0.0008780585,0.000424707,0.0003178266],"domain_scores_gemma":[0.9986698,0.00002317807,0.00008551078,0.000916492,0.0001606197,0.0001443826],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002636696,0.00007568874,0.0007835706,0.00007100003,0.00001793749,0.0001325683,0.00004740353,0.00000225353,0.9338247,0.00003062096,0.06065944,0.004328444],"study_design_scores_gemma":[0.000077135,0.00003525581,0.001002845,0.0000590629,0.000005162169,0.000110697,0.00002804491,0.0000376847,0.7324624,0.0004042115,0.2656828,0.00009473767],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958003,0.0006261954,0.0002339898,0.0004891452,0.001220398,0.0003543233,0.00002677337,0.0000295871,0.001219283],"genre_scores_gemma":[0.9935685,0.00005728557,0.0003247155,0.00005632983,0.0000868393,0.00006225899,0.000240181,0.00001872732,0.005585192],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2050233,"threshold_uncertainty_score":0.3645223,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01569794845194506,"score_gpt":0.3091459521603664,"score_spread":0.2934480037084213,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}