{"id":"W4392094712","doi":"10.1016/j.cccb.2024.100216","title":"Fluid biomarkers of the neurovascular unit in cerebrovascular disease and vascular cognitive disorders: A systematic review and meta-analysis","year":2024,"lang":"en","type":"review","venue":"Cerebral Circulation - Cognition and Behavior","topic":"Barrier Structure and Function Studies","field":"Neuroscience","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; National Health and Medical Research Council; University of New South Wales","keywords":"Medicine; Meta-analysis; Biomarker; Endothelial dysfunction; Stroke (engine); Internal medicine; Bioinformatics; Neurovascular bundle; Pathology; Oncology; Biology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01393293,0.002687068,0.01851295,0.00761578,0.0008266939,0.003588603,0.002048622,0.002126318,0.002917769],"category_scores_gemma":[0.03507384,0.001352554,0.03398704,0.009694664,0.0008295086,0.001691088,0.001698946,0.001463936,0.0003043947],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002647361,"about_ca_system_score_gemma":0.004479541,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008325166,"about_ca_topic_score_gemma":0.01734975,"domain_scores_codex":[0.9898511,0.004418416,0.003115673,0.00118343,0.001096604,0.0003348773],"domain_scores_gemma":[0.9746172,0.01917254,0.003463739,0.0007729951,0.001725916,0.0002476715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.001083853,0.00001989016,0.006946122,0.5205666,0.4589664,0.0001426082,0.0001069238,0.0004296286,0.0002099378,0.0001398777,0.0005746353,0.01081349],"study_design_scores_gemma":[0.0002430596,0.00014149,0.005294051,0.03994413,0.9522266,0.0001048173,0.00005367897,0.0001425736,0.0001036332,0.0001512122,0.001569499,0.00002527455],"study_design_candidate":"meta_analysis","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003511808,0.9949151,0.0004512161,0.000138521,0.00008279138,0.0001958374,0.0005351934,0.00001612068,0.0001533503],"genre_scores_gemma":[0.1424121,0.8513584,0.002474129,0.0007309233,0.0002459557,0.001338536,0.001146404,0.0000286561,0.00026493],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01851295,"threshold_uncertainty_score":0.07368523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09095379857896854,"score_gpt":0.3279341993482499,"score_spread":0.2369804007692813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}