{"id":"W4392111425","doi":"10.3390/cancers16050911","title":"Breast Tumor Metastasis and Its Microenvironment: It Takes Both Seed and Soil to Grow a Tumor and Target It for Treatment","year":2024,"lang":"en","type":"article","venue":"Cancers","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Research Institute in Oncology and Hematology; University of Manitoba; CancerCare Manitoba; Saskatchewan Cancer Agency; University of Saskatchewan; University of Alberta; University of Calgary","funders":"","keywords":"Breast cancer; Tumor microenvironment; Metastasis; Medicine; Immunotherapy; Metastatic breast cancer; Cancer research; Cancer; CA15-3; Primary tumor; Oncology; Melanoma; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003308812,0.0003271929,0.0006706237,0.0006495611,0.000471684,0.001785418,0.0003240597,0.0009513175,0.002566267],"category_scores_gemma":[0.0003623022,0.0001539515,0.0003016148,0.0005437277,0.0007387967,0.001137266,0.0006776649,0.001234336,0.001172483],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007648592,"about_ca_system_score_gemma":0.0009292021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001185174,"about_ca_topic_score_gemma":0.002219655,"domain_scores_codex":[0.9997289,0.00007236526,0.00001350142,0.00003460133,0.0001032763,0.00004741183],"domain_scores_gemma":[0.9998614,0.0000333229,0.0000272724,0.0000062681,0.00003492364,0.0000368532],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000204615,0.0001571351,0.003821741,0.005562664,0.0001101867,0.002901078,0.0005030386,0.0007936727,0.07576589,0.04990223,0.07134364,0.7889341],"study_design_scores_gemma":[0.00002711574,0.0002960611,0.006280003,0.001157766,0.00007591074,0.01251815,0.0006377857,0.0006500878,0.01832614,0.01356352,0.9464218,0.00004558179],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.008680597,0.951566,0.004543937,0.0158718,0.001330088,0.00003452593,0.00009716635,0.0001079469,0.01776797],"genre_scores_gemma":[0.09528108,0.8755224,0.005433741,0.004300977,0.002142901,0.00007894989,0.0001579616,0.00003958168,0.01704242],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.002566267,"threshold_uncertainty_score":0.008585036,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01697910033214917,"score_gpt":0.2631717073181842,"score_spread":0.246192606986035,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}