{"id":"W4392131574","doi":"10.1007/s00412-024-00817-x","title":"Chromatin organization and behavior in HRAS-transformed mouse fibroblasts","year":2024,"lang":"en","type":"article","venue":"Chromosoma","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Japan Society for the Promotion of Science; Takeda Science Foundation; Canada Research Chairs; Naito Foundation","keywords":"Chromatin; Biology; Cell biology; Nucleosome; Histone; Heterochromatin; Mitosis; CTCF; Cancer cell; DNA; Genetics; Transcription factor; Cancer; Gene; Enhancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369568,0.0001856501,0.0001729874,0.0004735965,0.0002891904,0.0003977451,0.000265693,0.0002327445,0.001780141],"category_scores_gemma":[0.0001246827,0.0002257258,0.0002476823,0.0002671069,0.0002614968,0.0001769556,0.0001574376,0.0004918198,0.0005384008],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004293744,"about_ca_system_score_gemma":0.0002321729,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005449029,"about_ca_topic_score_gemma":0.005939599,"domain_scores_codex":[0.9998249,0.00002566127,0.00001741443,0.00004516054,0.00005135008,0.00003555254],"domain_scores_gemma":[0.9997769,0.00005883996,0.00004548621,0.00004103882,0.00002140944,0.000056286],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008990778,0.00001290915,0.0003042643,0.000005241352,0.000002477937,0.00003815109,0.0000258367,0.00004164585,0.998996,0.0001037292,0.00001264268,0.0003672504],"study_design_scores_gemma":[0.00001161423,0.0001067016,0.01685288,0.000002528959,0.000009230078,0.0001951907,0.0000838552,0.0009567582,0.9805968,0.0000707309,0.001107692,0.000005959244],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943914,0.0006407002,0.002026822,0.00006412122,0.00002264128,0.00001388136,0.0007737723,0.00008357338,0.001983057],"genre_scores_gemma":[0.9914723,0.0002986339,0.001121542,0.00003504254,0.000007482407,0.00002171496,0.000763409,0.00004447283,0.006235527],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005449029,"threshold_uncertainty_score":0.01083463,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003722647176741375,"score_gpt":0.2119779564958584,"score_spread":0.208255309319117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}