{"id":"W4392162893","doi":"10.3390/genes15030292","title":"Translation of Data from Animal Models of Cancer to Immunotherapy of Breast Cancer and Chronic Lymphocytic Leukemia","year":2024,"lang":"en","type":"article","venue":"Genes","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research; Breast Cancer Research Foundation","keywords":"Chronic lymphocytic leukemia; Cancer; Immunotherapy; Breast cancer; Medicine; Leukemia; Translation (biology); Cancer immunotherapy; Cancer research; Oncology; Immunology; Internal medicine; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001545002,0.0001268366,0.000378115,0.0001295126,0.00001445793,0.000008344643,0.0002154514,0.0000826281,0.000311838],"category_scores_gemma":[0.000004410148,0.0001060181,0.00005068473,0.0002858059,0.0001298531,0.0001609593,0.00008866973,0.00006123761,0.000002375926],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.009276832,"about_ca_system_score_gemma":0.02121942,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05757568,"about_ca_topic_score_gemma":0.001738923,"domain_scores_codex":[0.9987126,0.00002141495,0.000359685,0.0003422547,0.0003708676,0.0001931827],"domain_scores_gemma":[0.9991165,0.00009954897,0.00005875236,0.0005451764,0.0001068497,0.00007320099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001286619,0.00001812233,0.0003256229,0.001497023,0.0005042673,0.00001002952,0.001164115,0.005566834,0.7126091,0.00005635437,0.0002796732,0.2766822],"study_design_scores_gemma":[0.007866733,0.0002256354,0.00376334,0.001529041,0.0002456022,0.00003167957,0.00008471456,0.8168994,0.1680176,0.0001250731,0.001062447,0.0001487305],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.858069,0.1395019,0.0004380884,0.000191416,0.00007447033,0.0003040317,0.001336848,0.00001756848,0.00006666379],"genre_scores_gemma":[0.9849077,0.01404459,0.0006067901,0.00002528617,0.0001912665,0.00002657278,0.00006160191,0.00003264241,0.0001035216],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8113325,"threshold_uncertainty_score":0.9945264,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0669658302962418,"score_gpt":0.370549523084018,"score_spread":0.3035836927877762,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}