{"id":"W4392169314","doi":"10.1002/cctc.202400182","title":"An Overview of Syntheses of Salvinorin A and its Analogues","year":2024,"lang":"en","type":"article","venue":"ChemCatChem","topic":"Chemical synthesis and alkaloids","field":"Chemistry","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; κ-opioid receptor; Hallucinogen; Stereochemistry; Combinatorial chemistry; Agonist; Receptor; Biology; Pharmacology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003334183,0.0009363975,0.0006547216,0.002042612,0.0006313926,0.0004147057,0.0004447122,0.0004050641,0.0102232],"category_scores_gemma":[0.0003601968,0.0003687169,0.0005654077,0.001502448,0.0002588745,0.001184152,0.0006419133,0.001121432,0.005284488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004226741,"about_ca_system_score_gemma":0.0005356721,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006507858,"about_ca_topic_score_gemma":0.001141482,"domain_scores_codex":[0.9998037,0.00002721359,0.00002640372,0.00004591131,0.00006550397,0.00003118581],"domain_scores_gemma":[0.9999113,0.00001795753,0.00001946963,0.0000117767,0.0000253193,0.00001430185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003655759,0.0008030044,0.0006926015,0.02848997,0.0004073408,0.002597856,0.0008091225,0.006766409,0.2849604,0.02881471,0.03306063,0.6122324],"study_design_scores_gemma":[0.0000666348,0.001185556,0.001433063,0.001057039,0.0001995479,0.002337428,0.000167951,0.001241516,0.104668,0.00589483,0.8816228,0.0001256542],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05672165,0.7711789,0.03686181,0.00137026,0.001705615,0.0005813083,0.002979568,0.0007123792,0.1278886],"genre_scores_gemma":[0.235011,0.7033487,0.02408594,0.0009915169,0.0008337772,0.0005003529,0.00268143,0.0002274264,0.03231984],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.0102232,"threshold_uncertainty_score":0.03420007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06427648038929888,"score_gpt":0.3123068655589651,"score_spread":0.2480303851696662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}