{"id":"W4392172698","doi":"10.1016/j.mucimm.2024.02.002","title":"The intestinal microbiota modulates the transcriptional landscape of iNKT cells at steady-state and following antigen exposure","year":2024,"lang":"en","type":"article","venue":"Mucosal Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Foundation for Innovation","keywords":"Biology; CD1D; Immunology; Immune system; Cell biology; Homeostasis; Inflammation; Effector; Gut flora; Cell; Colitis; Innate immune system; T cell; Natural killer T cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003348136,0.0001968737,0.0002213366,0.00009932602,0.0004922725,0.00005390605,0.0002406486,0.0001799074,0.0005142572],"category_scores_gemma":[0.0000342082,0.000116968,0.0001727568,0.0001421238,0.0004513567,0.0001134806,0.0001266893,0.0004960916,0.0004359537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003627342,"about_ca_system_score_gemma":0.00004551174,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007815281,"about_ca_topic_score_gemma":0.00003511679,"domain_scores_codex":[0.9986989,0.0002713709,0.0003930387,0.0002739393,0.00003503071,0.0003277045],"domain_scores_gemma":[0.9991848,0.0004031247,0.00008803184,0.0002565495,0.00005736589,0.00001008316],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003021895,0.00003280055,0.0007853772,0.00001675152,0.0005417706,0.000005686611,0.0009985885,0.000006603437,0.9885691,0.0006881898,0.003685396,0.004367576],"study_design_scores_gemma":[0.001202694,0.0005606778,0.03561475,0.0001215679,0.0001247245,0.0007691396,0.001491769,0.0001420725,0.5294216,0.0002602416,0.4299982,0.0002925789],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9296834,0.06220542,0.0001077213,0.0009122131,0.006055655,0.00018732,0.00001286126,0.00006119717,0.0007741723],"genre_scores_gemma":[0.9806906,0.001248606,0.00001570118,0.00009362472,0.00002389828,0.00001612296,0.00006881622,0.00002081303,0.01782184],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4591475,"threshold_uncertainty_score":0.5630755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008396934967806562,"score_gpt":0.2128720403347286,"score_spread":0.204475105366922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}