{"id":"W4392189042","doi":"10.3390/biomedicines12030533","title":"100 Years since the Discovery of Insulin, from Its Discovery to the Insulins of the Future","year":2024,"lang":"en","type":"article","venue":"Biomedicines","topic":"Diabetes Management and Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Ketonuria; Glycosuria; Medicine; Diabetes mellitus; Insulin; Disease; Intensive care medicine; Pediatrics; Internal medicine; Endocrinology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003826954,0.0001282964,0.0002410392,0.0001360642,0.00005847352,0.00005210553,0.0005136016,0.00005745877,0.00003403143],"category_scores_gemma":[0.0001586276,0.00004609851,0.0001406059,0.001169055,0.0003506274,0.0001315097,0.0003242312,0.0002175423,0.00003314698],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002279658,"about_ca_system_score_gemma":0.0001258697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001077015,"about_ca_topic_score_gemma":0.00005113153,"domain_scores_codex":[0.9985541,0.00006386499,0.0002799107,0.0002170322,0.000680665,0.0002044365],"domain_scores_gemma":[0.9989563,0.0002558822,0.0000617982,0.000608504,0.00007112652,0.00004643872],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001066257,0.001036366,0.03805901,0.003104457,0.002649902,0.0001423837,0.01327573,0.00004137587,0.1772016,0.01623071,0.4640044,0.2831878],"study_design_scores_gemma":[0.0007174259,0.0003634213,0.4477828,0.001497451,0.0003177169,0.0000018262,0.002488743,0.0002608189,0.005472394,0.0003562614,0.5406186,0.0001225667],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.891427,0.01798433,0.00005404731,0.08645926,0.002219135,0.0007476543,0.0001432011,0.00002531955,0.0009399921],"genre_scores_gemma":[0.9885651,0.0007169889,0.00001629495,0.001012399,0.001948951,0.00001768045,0.00002356255,0.0000197156,0.007679234],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4097238,"threshold_uncertainty_score":0.1879843,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01651442271071569,"score_gpt":0.2894772624737216,"score_spread":0.2729628397630059,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}