{"id":"W4392198225","doi":"10.1038/s41467-024-46141-x","title":"Global fungal-host interactome mapping identifies host targets of candidalysin","year":2024,"lang":"en","type":"article","venue":"Nature Communications","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Program of Shanghai Academic Research Leader; Shanghai Jiao Tong University; Science and Technology Commission of Shanghai Municipality; National Natural Science Foundation of China","keywords":"Interactome; Host (biology); Computational biology; Host response; Biology; Computer science; Genetics; Gene; Immune system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001287785,0.0003708245,0.0003581117,0.0006358639,0.0002502323,0.0003608543,0.0001559444,0.0002229693,0.001732378],"category_scores_gemma":[0.0001135444,0.0001053374,0.0003327835,0.0004870887,0.0001103011,0.0001670805,0.0003792175,0.0002477218,0.0003587434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002047151,"about_ca_system_score_gemma":0.0001532485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004420042,"about_ca_topic_score_gemma":0.001103495,"domain_scores_codex":[0.9998719,0.00001189108,0.000007260391,0.0000420951,0.00003968954,0.00002713337],"domain_scores_gemma":[0.9999263,0.00001806189,0.00001989014,0.000007521191,0.000008860311,0.0000193035],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001925408,0.00002011102,0.00304046,0.00007853266,0.00003391521,0.0001489135,0.00001592507,0.0001721635,0.9936469,0.00007313728,0.00009442912,0.002482963],"study_design_scores_gemma":[0.000035371,0.0003323823,0.1734369,0.00001702735,0.0001685222,0.001973029,0.0001552052,0.007660557,0.8090468,0.0002349033,0.006918717,0.00002058659],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890953,0.00162592,0.004937994,0.00006119232,0.000007751094,0.00002740161,0.00309885,0.00013177,0.001013829],"genre_scores_gemma":[0.9864833,0.0007070617,0.006384077,0.00004431733,0.000004921134,0.00004213392,0.004844402,0.00002695295,0.001462756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001732378,"threshold_uncertainty_score":0.00579536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02198497588924153,"score_gpt":0.3469006128535927,"score_spread":0.3249156369643512,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}