{"id":"W4392210498","doi":"10.2218/gtopdb/f799/2023.3","title":"Hydrolases & Lipases in GtoPdb v.2023.3","year":2023,"lang":"en","type":"article","venue":"IUPHAR/BPS Guide to Pharmacology CITE","topic":"Diabetes Management and Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lipase; Chemistry; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.001001342,0.0002747749,0.000499995,0.001439765,0.0001049997,0.00004056278,0.0003595717,0.0001362304,0.005409734],"category_scores_gemma":[0.0002760295,0.0002542596,0.0001450412,0.001997015,0.0001369574,0.0001476646,0.0004430469,0.0004454656,0.0120722],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001348391,"about_ca_system_score_gemma":0.0001225388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006789595,"about_ca_topic_score_gemma":0.0000663568,"domain_scores_codex":[0.9971656,0.0001653967,0.0005267787,0.0006067572,0.0004642395,0.001071225],"domain_scores_gemma":[0.9986946,0.0003516699,0.00006312561,0.0003521017,0.0001038596,0.0004346345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000310307,0.000266131,0.02488457,0.0001543995,0.0001904652,0.0008573508,0.0001395269,0.0002998879,0.07277162,0.00004049576,0.8906844,0.009400868],"study_design_scores_gemma":[0.003622203,0.0002410096,0.02723786,0.00008036968,0.0001409966,0.000007653526,0.00004380535,0.0007563636,0.008051313,0.00006815389,0.9594695,0.0002807991],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9416931,0.0004149275,0.0000248214,0.01754972,0.001203528,0.001378265,0.00005682141,0.0004910191,0.03718774],"genre_scores_gemma":[0.637265,0.0005937269,0.0004439627,0.02032302,0.001329038,0.0007198527,0.0004048713,0.0001012295,0.3388193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3044281,"threshold_uncertainty_score":0.9999909,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04657321893420474,"score_gpt":0.4355460019883402,"score_spread":0.3889727830541355,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}