{"id":"W4392210732","doi":"10.2196/54178","title":"Comparison of the Real-World Reporting of Symptoms and Well-Being for the HER2-Directed Trastuzumab Biosimilar Ogivri With Registry Data for Herceptin in the Treatment of Breast Cancer: Prospective Observational Study (OGIPRO) of Electronic Patient-Reported Outcomes","year":2024,"lang":"en","type":"article","venue":"JMIR Cancer","topic":"HER2/EGFR in Cancer Research","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Universität Zürich; Swiss Tumor Institute","keywords":"Biosimilar; Trastuzumab; Medicine; Observational study; Breast cancer; Clinical trial; Human Epidermal Growth Factor Receptor 2; Oncology; Internal medicine; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01062264,0.0004777152,0.0006887089,0.001440243,0.0003591688,0.001384794,0.0008112519,0.0008500954,0.001363702],"category_scores_gemma":[0.02331791,0.000311902,0.001464848,0.002200379,0.0005293115,0.001195979,0.001468204,0.001118773,0.0003561859],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007027157,"about_ca_system_score_gemma":0.0006661151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001462088,"about_ca_topic_score_gemma":0.001576249,"domain_scores_codex":[0.9895076,0.00537861,0.001695253,0.001612638,0.001404918,0.0004010262],"domain_scores_gemma":[0.9600063,0.008312151,0.0243992,0.003066091,0.002895485,0.001320729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005455305,0.0004215854,0.9881467,0.0001796925,0.001313307,0.00003371754,0.0002475237,0.0001492935,0.0001907365,0.0000842615,0.0004756652,0.003302097],"study_design_scores_gemma":[0.0006752502,0.002186329,0.9939191,0.00006909011,0.0005906269,0.0002132469,0.0003416561,0.0006101305,0.0002098996,0.00006504791,0.001091085,0.00002848948],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940838,0.0005795906,0.0003969893,0.00006936739,0.0000210918,0.0002253655,0.003934368,0.000008706882,0.0006807584],"genre_scores_gemma":[0.9917494,0.0002254955,0.0003528247,0.00009131604,0.00003012016,0.0003239615,0.007096678,0.000007724896,0.0001225178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01062264,"threshold_uncertainty_score":0.05617851,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278437417289211,"score_gpt":0.4706072347069483,"score_spread":0.3427634929780272,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}