{"id":"W4392222236","doi":"10.1186/s13068-024-02477-6","title":"Biocatalytic cascade to polysaccharide amination","year":2024,"lang":"en","type":"article","venue":"Biotechnology for Biofuels and Bioproducts","topic":"Enzyme Catalysis and Immobilization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"University of Toronto; Natural Sciences and Engineering Research Council of Canada; Helsingin Yliopisto","keywords":"Amination; Polysaccharide; Cascade; Reductive amination; Polymer science; Chemistry; Organic chemistry; Chromatography; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000186833,0.000165443,0.0001322251,0.0002272225,0.00008911601,0.00005842175,0.0001418891,0.000348087,0.00000365037],"category_scores_gemma":[0.0001750854,0.0001412204,0.00006105391,0.0003908444,0.0001135757,0.000008395718,0.0001121383,0.00006554965,0.00001976265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001493017,"about_ca_system_score_gemma":0.00003623342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001020206,"about_ca_topic_score_gemma":0.00001370925,"domain_scores_codex":[0.9988078,0.00000763854,0.0001813864,0.0006969644,0.00006239245,0.0002438142],"domain_scores_gemma":[0.9995047,0.000006592812,0.0000301208,0.0003389204,0.00005809186,0.00006158982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001892464,0.00002055097,0.00002831834,0.00008580671,0.00004011405,0.000001136684,0.00002019014,8.510904e-7,0.9496646,0.002117893,0.001804228,0.04619738],"study_design_scores_gemma":[0.000103943,0.0003358055,0.0001432269,0.00002129662,0.00003064795,0.00003173064,0.00003590206,0.00006775979,0.8503296,0.0002621725,0.148463,0.0001748335],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9785166,0.008402169,0.005282165,0.006627062,0.000426504,0.0005094644,0.00009507582,0.0001135082,0.00002748256],"genre_scores_gemma":[0.9957578,0.0007366729,0.00110844,0.000260163,0.0003083638,0.00006512335,0.0002739138,0.0000285677,0.001461012],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1466588,"threshold_uncertainty_score":0.5758802,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00957127983446042,"score_gpt":0.2584424800539861,"score_spread":0.2488712002195257,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}