{"id":"W4392246407","doi":"10.1016/j.chom.2024.02.003","title":"Inflammation and bacteriophages affect DNA inversion states and functionality of the gut microbiota","year":2024,"lang":"en","type":"article","venue":"Cell Host & Microbe","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Institute for Advanced Research","funders":"H2020 European Research Council; National Institute of Diabetes and Digestive and Kidney Diseases; Israel Cancer Research Fund; Israel Science Foundation; Human Frontier Science Program; Canadian Institute for Advanced Research","keywords":"Biology; Gut flora; Affect (linguistics); Inflammation; Inversion (geology); Microbiology; DNA; Computational biology; Genetics; Immunology; Communication","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000134132,0.0001112176,0.00009547659,0.00002891158,0.00008582631,0.00003787527,0.00006655704,0.0001032333,0.00002067481],"category_scores_gemma":[0.000007315217,0.00008369585,0.0000457851,0.00006300597,0.0001276916,0.000006098904,0.0001544045,0.0000772304,0.000005541878],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001255907,"about_ca_system_score_gemma":0.00005814391,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004621439,"about_ca_topic_score_gemma":0.00003778204,"domain_scores_codex":[0.9994052,0.00005411759,0.0001398936,0.0002416772,0.00003383222,0.0001252926],"domain_scores_gemma":[0.9997006,0.00001569351,0.00004982422,0.0001634856,0.00003336027,0.00003702176],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002096109,0.00001105997,0.001867911,0.0004096666,0.00001525822,5.040416e-7,0.0001442792,6.248323e-7,0.99333,0.00001077661,0.00351827,0.0006706627],"study_design_scores_gemma":[0.0002028818,0.00007002513,0.06526833,0.00006310463,0.00002249422,0.00001563213,0.00005410699,0.0000097865,0.8837615,0.000012668,0.05043073,0.00008877079],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9939566,0.005049767,0.00002538035,0.0004063415,0.0001956919,0.0001727642,0.0000790659,0.000008170813,0.0001062257],"genre_scores_gemma":[0.9969463,0.00147085,0.00008546756,0.00012929,0.00007258305,0.000002020386,0.0001263403,0.00001213109,0.001154973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1095686,"threshold_uncertainty_score":0.3413018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004565862700512958,"score_gpt":0.2172319018498815,"score_spread":0.2126660391493686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}