{"id":"W4392285232","doi":"10.3390/biomedicines12030550","title":"Double Trouble: How Microbiome Dysbiosis and Mitochondrial Dysfunction Drive Non-Alcoholic Fatty Liver Disease and Non-Alcoholic Steatohepatitis","year":2024,"lang":"en","type":"article","venue":"Biomedicines","topic":"Liver Disease Diagnosis and Treatment","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Children's Hospital of Eastern Ontario; University of Alberta; University of Ottawa","funders":"King Abdullah University of Science and Technology","keywords":"Steatohepatitis; Dysbiosis; Fatty liver; Microbiome; Steatosis; Alcoholic liver disease; Biology; Disease; Bioinformatics; Immunology; Medicine; Cirrhosis; Internal medicine; Endocrinology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006567602,0.0005560674,0.0009168976,0.0006755862,0.0004518954,0.001739782,0.0004454039,0.001242359,0.002402438],"category_scores_gemma":[0.0008913123,0.000179618,0.0006533387,0.0005029159,0.0006896277,0.001584325,0.001074334,0.001533192,0.0006575872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005971959,"about_ca_system_score_gemma":0.001189752,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000976148,"about_ca_topic_score_gemma":0.001864648,"domain_scores_codex":[0.9995859,0.0001335009,0.00004065565,0.00008366743,0.0000894237,0.00006695552],"domain_scores_gemma":[0.9997123,0.00007465337,0.00006673689,0.000011374,0.00007783219,0.00005711326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.001067357,0.000173734,0.01071652,0.01813969,0.00104897,0.003830269,0.001368023,0.001246293,0.05588341,0.03185372,0.07696673,0.7977053],"study_design_scores_gemma":[0.00007041589,0.0006781893,0.01921126,0.005768434,0.0008135164,0.009744728,0.001675061,0.001091772,0.01220893,0.02705729,0.9215515,0.0001289341],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01162726,0.9650635,0.002498711,0.01162441,0.003285527,0.00002922135,0.0001525977,0.00008811236,0.005630623],"genre_scores_gemma":[0.09214037,0.8901998,0.002536164,0.006741966,0.002143623,0.00004252901,0.0001990871,0.00002833286,0.00596816],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002402438,"threshold_uncertainty_score":0.008036911,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01404161860827414,"score_gpt":0.2506703333877749,"score_spread":0.2366287147795008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}