{"id":"W4392351520","doi":"10.1101/2024.03.01.582966","title":"Omega-3 polyunsaturated fatty acids modify glucose metabolism in THP-1 monocytes","year":2024,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Fatty Acid Research and Health","field":"Nursing","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Oxidative phosphorylation; Docosahexaenoic acid; Glycolysis; Biochemistry; Pyruvate dehydrogenase complex; Metabolism; Biology; Fatty acid metabolism; Carbohydrate metabolism; Beta oxidation; Pyruvate kinase; Fatty acid; Polyunsaturated fatty acid; Chemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001282286,0.0002386625,0.0002653249,0.0002268612,0.0002210519,0.000304944,0.00009328522,0.0001979404,0.001741002],"category_scores_gemma":[0.00008913114,0.0001164891,0.0002599261,0.0003111754,0.0001451086,0.0001024342,0.0001717709,0.0004054435,0.0005115531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001330039,"about_ca_system_score_gemma":0.0001127375,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005622118,"about_ca_topic_score_gemma":0.0006979653,"domain_scores_codex":[0.999826,0.00003750677,0.00001948765,0.0000317959,0.00003707819,0.0000480775],"domain_scores_gemma":[0.9999359,0.00001297943,0.00001188721,0.00000850981,0.00002026492,0.00001051625],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001158275,0.00007717041,0.00192516,0.00009751785,0.00001336348,0.0001121789,0.0000710469,0.00005065301,0.9942541,0.00003624197,0.00009983146,0.002104599],"study_design_scores_gemma":[0.0001315514,0.001971093,0.07486493,0.00004188124,0.0001014435,0.000334396,0.0005755772,0.00102717,0.9166551,0.0002829405,0.003988154,0.00002578027],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9911522,0.002526997,0.002163698,0.0002059605,0.0001225213,0.00004376186,0.002193708,0.00003277105,0.001558371],"genre_scores_gemma":[0.9889132,0.001864718,0.003982456,0.0003317292,0.0000392319,0.0001286266,0.001284746,0.00001190479,0.003443319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001741002,"threshold_uncertainty_score":0.005824208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02357774691347158,"score_gpt":0.2748590684126164,"score_spread":0.2512813214991448,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}