{"id":"W4392359678","doi":"10.1186/s12967-024-05024-x","title":"Thyroid hormone protects human lung epithelial cells from cold preservation and warm reperfusion-induced injury","year":2024,"lang":"en","type":"article","venue":"Journal of Translational Medicine","topic":"Transplantation: Methods and Outcomes","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Toronto General Hospital Research Institute, University Health Network; Canadian Institutes of Health Research; Government of Ontario","keywords":"Viability assay; Apoptosis; Transplantation; Inflammation; Transcriptome; Reperfusion injury; Downregulation and upregulation; Lung; Cell; Hormone; Medicine; Chemistry; Cell biology; Pharmacology; Biology; Gene expression; Immunology; Internal medicine; Ischemia; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001920024,0.0002672402,0.000268872,0.000215411,0.0002068834,0.0003038415,0.0001521019,0.0002234803,0.001244871],"category_scores_gemma":[0.0001898578,0.00008444273,0.0005107326,0.00021414,0.0002085335,0.0001311704,0.0001817954,0.0002865351,0.0002937045],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002421986,"about_ca_system_score_gemma":0.0004536925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001792036,"about_ca_topic_score_gemma":0.001937206,"domain_scores_codex":[0.999872,0.00002010352,0.0000168037,0.00002673198,0.00003275611,0.00003162981],"domain_scores_gemma":[0.9999059,0.00001499525,0.00002030455,0.00001850102,0.00002446298,0.00001585053],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006236735,0.00004288536,0.0009023536,0.00009965365,0.00001929291,0.00006138447,0.00003182304,0.00005962128,0.9957387,0.00001781992,0.00005438217,0.002348378],"study_design_scores_gemma":[0.00007138636,0.002447134,0.02183874,0.00002862474,0.0001078305,0.0003826495,0.0001624982,0.0004697607,0.9691063,0.00005609092,0.005317178,0.0000118218],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874455,0.009364971,0.001491917,0.0001258439,0.0000819763,0.00004387675,0.000404275,0.00005778324,0.0009838943],"genre_scores_gemma":[0.9949121,0.001983429,0.000889984,0.00008497151,0.00001815605,0.00004056206,0.0006873953,0.00001256325,0.001370805],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001792036,"threshold_uncertainty_score":0.004164517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03043971526805447,"score_gpt":0.3401139161622436,"score_spread":0.3096742008941891,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}