{"id":"W4392361470","doi":"10.3390/curroncol31030098","title":"Real-World Analysis of the Clinical and Economic Impact of the 21-Gene Recurrence Score (RS) in Invasive Lobular Early-Stage Breast Carcinoma in Ireland","year":2024,"lang":"en","type":"article","venue":"Current Oncology","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Breast cancer; Internal medicine; Stage (stratigraphy); Chemotherapy; Population; Hormone therapy; Oncology; Breast carcinoma; Cancer; Observational study; Invasive lobular carcinoma; Lymph node; Gastroenterology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.006357131,0.0003544757,0.00048338,0.0009808639,0.0002057399,0.001572304,0.001105099,0.0006846227,0.001480064],"category_scores_gemma":[0.02210384,0.0003578612,0.001118959,0.00192831,0.0007146618,0.001016923,0.001343105,0.001088161,0.0003521254],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003291374,"about_ca_system_score_gemma":0.001199654,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02779622,"about_ca_topic_score_gemma":0.0214016,"domain_scores_codex":[0.9951975,0.003088846,0.0003731942,0.0004610237,0.0003462178,0.000533275],"domain_scores_gemma":[0.9778286,0.008176032,0.01074683,0.00113972,0.001062318,0.001046515],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009211938,0.0001291905,0.9853254,0.00006816945,0.0002697232,0.0001822629,0.00006694644,0.009385484,0.00005003004,0.000166517,0.0007441269,0.002691019],"study_design_scores_gemma":[0.0000948397,0.0004896192,0.9708499,0.00005434725,0.0001248219,0.0003675522,0.0006736051,0.02589092,0.0001197425,0.000264818,0.001029271,0.00004062622],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942328,0.0002427138,0.000280427,0.0003848379,0.00001288203,0.00003137587,0.00431765,0.000006924337,0.000490316],"genre_scores_gemma":[0.9971781,0.00007389677,0.0001616293,0.00004271086,0.000008525651,0.00002052846,0.002413693,0.000002962287,0.0000978777],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02779622,"threshold_uncertainty_score":0.05526882,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05830359939233077,"score_gpt":0.3906755060929957,"score_spread":0.3323719067006649,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}