{"id":"W4392369497","doi":"10.1158/1538-7445.ovarian23-a109","title":"Abstract A109: Novel germline genetic variants in pseudogenes associated with overall survival in advanced stage ovarian cancer treated with carboplatin, paclitaxel, and bevacizumab: Results from the ROSiA trial","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sunnybrook Health Science Centre; Western University; Princess Margaret Cancer Centre; University of Toronto","funders":"","keywords":"Carboplatin; Paclitaxel; Bevacizumab; Germline; Oncology; Medicine; Ovarian cancer; Internal medicine; Stage (stratigraphy); Cancer; Chemotherapy; Biology; Gene; Genetics; Cisplatin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001317956,0.0004391854,0.0004655589,0.0001300514,0.000252453,0.0007374922,0.000423335,0.0005767142,0.002535679],"category_scores_gemma":[0.002043535,0.0001374151,0.001085182,0.0003047437,0.0002878332,0.0002279216,0.0002876348,0.0008204479,0.0003047266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002058703,"about_ca_system_score_gemma":0.0002804611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007271622,"about_ca_topic_score_gemma":0.001105167,"domain_scores_codex":[0.9994202,0.0002913646,0.00004931518,0.0001491501,0.00005069414,0.0000392977],"domain_scores_gemma":[0.9986237,0.0006194055,0.0003828437,0.0001286418,0.00007456327,0.00017082],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.3438523,0.002058893,0.5381367,0.0008261328,0.01109028,0.001232021,0.0002580406,0.00362343,0.04644524,0.0007314096,0.00880624,0.04293943],"study_design_scores_gemma":[0.06859618,0.02194227,0.8576011,0.0001519036,0.02056142,0.0019879,0.0002206699,0.00789939,0.007872081,0.002347737,0.01071913,0.0001002547],"study_design_candidate":"randomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950438,0.0008566191,0.0004154675,0.000405472,0.00006957954,0.00008648122,0.002283601,0.00003659884,0.000802346],"genre_scores_gemma":[0.9956806,0.0001806879,0.0006113811,0.0002502672,0.00009653567,0.00008558077,0.00265024,0.00001887606,0.0004258429],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002535679,"threshold_uncertainty_score":0.008482635,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08140658505046139,"score_gpt":0.3784360474014882,"score_spread":0.2970294623510268,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}