{"id":"W4392372579","doi":"10.26434/chemrxiv-2024-g1gsh","title":"N-to-S acyl transfer as an enabling strategy in asymmetric and chemoenzymatic synthesis","year":2024,"lang":"en","type":"preprint","venue":"ChemRxiv","topic":"Chemical Reactions and Isotopes","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institutes of Health; York University; New York University Abu Dhabi","keywords":"Business; Chemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004319954,0.0003510457,0.0001611851,0.000164024,0.0001359288,0.0002730393,0.0003370826,0.0003491752,0.0004975126],"category_scores_gemma":[0.0001779703,0.0001628573,0.0001869443,0.000158953,0.0005064199,0.0004190952,0.0003522102,0.0005384117,0.0003988219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004048233,"about_ca_system_score_gemma":0.0003316493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002932593,"about_ca_topic_score_gemma":0.0003804945,"domain_scores_codex":[0.9998454,0.00003573394,0.00001629614,0.00003214379,0.00004809256,0.00002236358],"domain_scores_gemma":[0.9999105,0.00001731869,0.00002883696,0.00002085124,0.00001054838,0.00001206687],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006359768,0.00002909022,0.0001190059,0.00009464448,0.000004131894,0.0001588738,0.00005563013,0.0005454078,0.9819964,0.006719573,0.0001724323,0.01004123],"study_design_scores_gemma":[0.00001529727,0.0001742759,0.0001655992,0.000005795231,0.000004693707,0.0002595552,0.000009848557,0.001734585,0.9878157,0.0004827073,0.009323649,0.000008292763],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7874309,0.007143894,0.1814316,0.0008859459,0.0002007062,0.0001872996,0.0002598228,0.0008819652,0.02157788],"genre_scores_gemma":[0.9384958,0.003641552,0.05155987,0.0001742652,0.00005431192,0.00009519057,0.0001714833,0.0000565904,0.005750943],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004975126,"threshold_uncertainty_score":0.002937198,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1135006182019615,"score_gpt":0.4223563815837045,"score_spread":0.3088557633817429,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}