{"id":"W4392376240","doi":"10.1158/1538-7445.ovarian23-a037","title":"Abstract A037: Exploring the therapeutic effectiveness of EO3001 in the treatment of clear cell ovarian cancers with ARID1A mutations","year":2024,"lang":"en","type":"article","venue":"Cancer Research","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"ARID1A; Ovarian cancer; Medicine; Oncology; Cancer research; Internal medicine; Cancer; Biology; Mutation; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005993533,0.00008214951,0.0001008816,0.00005343653,0.00006748496,0.00002341627,0.0001816741,0.0000355142,0.00001704678],"category_scores_gemma":[0.000006781156,0.00004310048,0.00005411226,0.000296731,0.0001743965,0.000004343492,0.00001416096,0.0001260935,0.00000129458],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001394876,"about_ca_system_score_gemma":0.0004936142,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002817377,"about_ca_topic_score_gemma":0.0006306376,"domain_scores_codex":[0.9990651,0.0001887673,0.0001221462,0.0002003881,0.0002354863,0.0001881185],"domain_scores_gemma":[0.9994024,0.0001829315,0.00002283608,0.0002839456,0.00008790019,0.00001997962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008724052,0.0001938539,0.0008487499,0.000700843,0.0002288916,0.00001461017,0.004756415,0.02458168,0.929407,0.0002540433,0.00006406205,0.03807746],"study_design_scores_gemma":[0.0009530938,0.001352183,0.01465437,0.0004618843,0.00004414406,0.000004986055,0.00293879,0.0006161814,0.9724311,0.0002714953,0.006135662,0.0001361362],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9906809,0.007922634,0.00007668731,0.0001245199,0.00007224453,0.0003583579,0.00002142378,0.000003751794,0.0007394331],"genre_scores_gemma":[0.9963667,0.002948387,0.00001332937,0.000008363752,0.00008814033,0.0004842843,0.00001014737,0.00001673912,0.0000639534],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0430241,"threshold_uncertainty_score":0.4259051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08906224066333106,"score_gpt":0.3898139217642079,"score_spread":0.3007516811008769,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}