{"id":"W4392387786","doi":"10.1016/j.jns.2024.122945","title":"Differing patterns of cortical grey matter pathology identified by multifractal analysis in UMN-predominant ALS patients with and without corticospinal tract hyperintensity","year":2024,"lang":"en","type":"article","venue":"Journal of the Neurological Sciences","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"","keywords":"Corticospinal tract; Upper motor neuron; Hyperintensity; Amyotrophic lateral sclerosis; Voxel-based morphometry; Cingulum (brain); Pyramidal tracts; Medicine; Magnetic resonance imaging; Primary motor cortex; Pathology; Motor cortex; White matter; Anatomy; Radiology; Internal medicine; Diffusion MRI; Fractional anisotropy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003409082,0.0003650048,0.0003221188,0.002063387,0.0004363167,0.0004881595,0.0002244697,0.0003482417,0.00218426],"category_scores_gemma":[0.001689135,0.0001568787,0.0002107128,0.0005906054,0.0005736694,0.0004502175,0.0004898655,0.0001780839,0.0002567897],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002802043,"about_ca_system_score_gemma":0.0002315643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003499088,"about_ca_topic_score_gemma":0.006436602,"domain_scores_codex":[0.9997737,0.00003627486,0.00003197605,0.00005534865,0.00003890871,0.00006391646],"domain_scores_gemma":[0.9994681,0.0001443283,0.0001884756,0.00003280345,0.00008025606,0.00008598214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001912174,0.00007886616,0.9164163,0.00004458808,0.0001890016,0.004597578,0.001621027,0.0002558448,0.06266665,0.0001770993,0.0001448807,0.01189604],"study_design_scores_gemma":[0.00000713205,0.00007671955,0.9965749,0.00000468124,0.00002541157,0.002125481,0.0002266968,0.0002570474,0.0005548393,0.000100088,0.00004270233,0.000004311902],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9995073,0.00005299622,0.00007829838,0.00001218334,0.000001171024,0.000002512398,0.00003755082,0.000002724698,0.0003052489],"genre_scores_gemma":[0.9997936,0.00001793919,0.00005490969,0.00000754653,0.000002636535,0.000001795832,0.00003668548,0.000002094705,0.00008280172],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003499088,"threshold_uncertainty_score":0.007307112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02252563632884429,"score_gpt":0.2986025897232414,"score_spread":0.2760769533943971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}