{"id":"W4392400555","doi":"10.14336/ad.2024.0103","title":"Glial Cell Activation and Immune Responses in Glaucoma: A Systematic Review of Human Postmortem Studies of the Retina and Optic Nerve","year":2024,"lang":"en","type":"review","venue":"Aging and Disease","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kensington Health","funders":"","keywords":"Neuroinflammation; Optic nerve; Retina; Pathology; Microglia; Glaucoma; Glial fibrillary acidic protein; Medicine; Immune system; Biology; Cell biology; Neuroscience; Immunology; Inflammation; Immunohistochemistry; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003426551,0.001145414,0.004827964,0.01301031,0.0004745029,0.001460467,0.001125713,0.001010233,0.00338759],"category_scores_gemma":[0.01285462,0.0006240482,0.003822898,0.01411903,0.0007588606,0.001511345,0.001141324,0.0005660569,0.0003052098],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001370294,"about_ca_system_score_gemma":0.005384734,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004878153,"about_ca_topic_score_gemma":0.01502316,"domain_scores_codex":[0.9969816,0.000627025,0.001566555,0.0002780065,0.000460261,0.00008653271],"domain_scores_gemma":[0.9846618,0.01053042,0.003177674,0.0002566725,0.001216855,0.0001566697],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002285233,0.00001435285,0.001508483,0.9321336,0.00408492,0.0003243213,0.0002600363,0.00006371819,0.0004143143,0.0001242832,0.001399515,0.05944415],"study_design_scores_gemma":[0.0001421083,0.0003655361,0.01747177,0.8770995,0.06244406,0.002272287,0.0005835477,0.00006385562,0.0004617854,0.0002802273,0.03875904,0.00005623708],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001098331,0.9981527,0.00006723722,0.00006793241,0.00003515241,0.00005749975,0.000381933,0.000003000053,0.0001363052],"genre_scores_gemma":[0.008474448,0.9904928,0.0003134726,0.0001494695,0.00004508049,0.0001221454,0.000324038,0.000002975358,0.00007568319],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01301031,"threshold_uncertainty_score":0.01812154,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06294526510562244,"score_gpt":0.3497771800816561,"score_spread":0.2868319149760337,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}