{"id":"W4392436355","doi":"10.1016/j.biopha.2024.116372","title":"Sense and anti-sense: Role of FAM83A and FAM83A-AS1 in Wnt, EGFR, PI3K, EMT pathways and tumor progression","year":2024,"lang":"en","type":"article","venue":"Biomedicine & Pharmacotherapy","topic":"Cancer-related molecular mechanisms research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":14,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Natural Science Foundation of China","keywords":"Wnt signaling pathway; Long non-coding RNA; Signal transduction; RNA; Cancer; Cancer research; Computer science; Biology; Cell biology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005692266,0.0007180492,0.0006860727,0.0006409694,0.0006440802,0.0006002117,0.0005127088,0.001279309,0.01695188],"category_scores_gemma":[0.0005711398,0.0004102717,0.0004948117,0.000825169,0.0008539342,0.0007727554,0.0004064154,0.001296069,0.00469785],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005979483,"about_ca_system_score_gemma":0.0006786333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009197241,"about_ca_topic_score_gemma":0.001395474,"domain_scores_codex":[0.9988067,0.000224936,0.0001140531,0.000478368,0.0002167339,0.000159161],"domain_scores_gemma":[0.999536,0.0001407362,0.00009777066,0.00005862187,0.0000759369,0.00009091838],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005275958,0.00006475706,0.000177045,0.0002360358,0.00001271271,0.0001889769,0.00006356859,0.00005886545,0.9928229,0.0008275148,0.001281081,0.003739008],"study_design_scores_gemma":[0.0001555058,0.0007340993,0.003532756,0.00005039334,0.00005920551,0.001166928,0.0002438096,0.0008996346,0.9384991,0.0006115939,0.05400941,0.00003754742],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8100129,0.01873187,0.06413985,0.006423747,0.007201518,0.0006304239,0.01508066,0.002910101,0.07486891],"genre_scores_gemma":[0.86661,0.008549903,0.06699807,0.003230581,0.0004853998,0.001060158,0.008034675,0.0005670943,0.04446405],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01695188,"threshold_uncertainty_score":0.05670971,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009203854034959753,"score_gpt":0.3198240936547219,"score_spread":0.3106202396197622,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}