{"id":"W4392456271","doi":"10.1016/j.cell.2024.02.005","title":"Neutrophil profiling illuminates anti-tumor antigen-presenting potency","year":2024,"lang":"en","type":"article","venue":"Cell","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":408,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Program of Shanghai Academic Research Leader; Science and Technology Commission of Shanghai Municipality; Chinese Academy of Sciences; National Natural Science Foundation of China","keywords":"Biology; Antigen; Immunology; Antigen presentation; Cancer immunotherapy; Immune system; Cancer; Neutrophil extracellular traps; Immunotherapy; Inflammation; Transcriptome; Cancer research; T cell; Gene; Genetics; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003070933,0.0002296825,0.0003338715,0.0004289483,0.0001457937,0.0007913347,0.0001685057,0.0003529546,0.002318904],"category_scores_gemma":[0.0003780525,0.0001071575,0.0001262379,0.0002573227,0.0001725722,0.0004121554,0.0003349262,0.0005208466,0.0005002836],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002176569,"about_ca_system_score_gemma":0.0001684311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002183012,"about_ca_topic_score_gemma":0.0004318994,"domain_scores_codex":[0.9997695,0.00005795046,0.00001245743,0.00005107432,0.00005565392,0.00005324613],"domain_scores_gemma":[0.9998559,0.00003317088,0.00003673286,0.00001319371,0.00002793801,0.00003308204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001260275,0.00006726128,0.02222096,0.0001620857,0.00003610538,0.000133101,0.00007254405,0.0002800213,0.9501696,0.0009530822,0.000524557,0.02412047],"study_design_scores_gemma":[0.0001246531,0.002379924,0.2109039,0.0001354328,0.0003104108,0.00225441,0.0006016197,0.008228521,0.7514495,0.003064785,0.02050776,0.00003905866],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.986735,0.004591681,0.003965778,0.0002618881,0.00005332572,0.0000419818,0.0008353909,0.00006339038,0.003451528],"genre_scores_gemma":[0.9951867,0.001440044,0.001439411,0.0001557988,0.00003984508,0.00002713648,0.0003042702,0.00001658401,0.001390193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002318904,"threshold_uncertainty_score":0.007757485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009691155251609584,"score_gpt":0.2367595479258055,"score_spread":0.227068392674196,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}