{"id":"W4392457594","doi":"10.7554/elife.86845.3.sa3","title":"Author Response: Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse","year":2024,"lang":"en","type":"peer-review","venue":"","topic":"Nuclear Structure and Function","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canadian Nautical Research Society","funders":"","keywords":"Centriole; Microtubule; Infertility; Cell biology; Biology; Male infertility; Genetics; Pregnancy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002101166,0.0005273874,0.0005204944,0.0005976466,0.00112785,0.001171928,0.0006998392,0.003786193,0.08845039],"category_scores_gemma":[0.01087381,0.0002780434,0.0003769993,0.0002671612,0.0007576885,0.0005643704,0.001232779,0.003013784,0.02829893],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001357559,"about_ca_system_score_gemma":0.00235436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003449637,"about_ca_topic_score_gemma":0.007296403,"domain_scores_codex":[0.9978514,0.0002989823,0.0001324795,0.0002572546,0.001169574,0.0002903886],"domain_scores_gemma":[0.991538,0.00168136,0.000433513,0.0003431575,0.004258689,0.001745305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001890094,0.0000188058,0.0005865643,0.000113526,0.00001247823,0.0006705421,0.0001132277,0.0001187661,0.004486106,0.000940643,0.986038,0.006712383],"study_design_scores_gemma":[0.00009735922,0.00009411548,0.003811742,0.0001032182,0.00001808377,0.0009672386,0.0007316364,0.0003061483,0.006809181,0.0008987652,0.9861075,0.00005508429],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.01644602,0.002139929,0.005593074,0.6251957,0.2845175,0.0003909933,0.004186483,0.003219315,0.05831105],"genre_scores_gemma":[0.06202872,0.002057654,0.0029171,0.1551863,0.01509383,0.0002059386,0.003570091,0.00083825,0.758102],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08845039,"threshold_uncertainty_score":0.2958961,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02246024788330877,"score_gpt":0.3146412291193273,"score_spread":0.2921809812360185,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}