{"id":"W4392461149","doi":"10.1007/7651_2024_517","title":"Assessment of Autophagy in Leishmania Parasites","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; Research Institute in Oncology and Hematology; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"","keywords":"Autophagy; Leishmania; Biology; Leishmaniasis; Cell biology; Acridine orange; Organelle; Intracellular parasite; Sandfly; Amastigote; Leishmania major; ATG8; Phagosome; Cutaneous leishmaniasis; Microbiology; Parasite hosting; Immunology; Intracellular; Apoptosis; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003911416,0.000336082,0.0003552652,0.0007667851,0.0005835354,0.0004534551,0.0002151286,0.0004563661,0.001843261],"category_scores_gemma":[0.0001754096,0.000209007,0.0003577795,0.0005750824,0.0003791698,0.0004817239,0.0004414229,0.0008924349,0.0005435873],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003087411,"about_ca_system_score_gemma":0.0002854915,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004513016,"about_ca_topic_score_gemma":0.0008273913,"domain_scores_codex":[0.9996318,0.00008979956,0.00004467032,0.00007624592,0.00007332652,0.00008418279],"domain_scores_gemma":[0.9998661,0.00002644383,0.00002295003,0.00001464538,0.00004155468,0.00002816977],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002484124,0.0000339573,0.0006459149,0.00010621,0.00001147364,0.00004268161,0.00006961143,0.00003186934,0.9971684,0.000252972,0.00003819808,0.001350254],"study_design_scores_gemma":[0.0000251143,0.0004292738,0.02043887,0.00003158559,0.00005961909,0.0006463702,0.0002338779,0.001201376,0.9727396,0.0003915865,0.003786372,0.00001624194],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.965357,0.006539722,0.01634469,0.0001985695,0.0001128579,0.0001338533,0.001280767,0.0001470139,0.009885442],"genre_scores_gemma":[0.9597092,0.003065698,0.02546975,0.0001407747,0.00004831375,0.0002800942,0.001858999,0.00008125146,0.009345901],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.001843261,"threshold_uncertainty_score":0.006166339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04430053332276897,"score_gpt":0.5032240432943427,"score_spread":0.4589235099715737,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}