{"id":"W4392477130","doi":"10.2139/ssrn.4745061","title":"Meta‑Analysis Study of the Therapeutic Impact of Mesenchymal Stem Cells Derived Exosomes for Chronic Kidney Diseases","year":2024,"lang":"en","type":"preprint","venue":"SSRN Electronic Journal","topic":"Extracellular vesicles in disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Discovery Centre","funders":"","keywords":"Microvesicles; Mesenchymal stem cell; Medicine; Exosome; Cancer research; Biology; microRNA; Pathology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.008821055,0.001872654,0.007788591,0.001466803,0.0005752,0.002862981,0.001381442,0.002189433,0.004260974],"category_scores_gemma":[0.01684557,0.0008892387,0.02794151,0.0026493,0.000576957,0.0011124,0.001483253,0.002178743,0.00051515],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005866404,"about_ca_system_score_gemma":0.000853981,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002688143,"about_ca_topic_score_gemma":0.002874963,"domain_scores_codex":[0.9898825,0.005162725,0.001381303,0.002461964,0.0006016754,0.0005097791],"domain_scores_gemma":[0.9859877,0.009731868,0.001540044,0.001746363,0.0005915863,0.0004024715],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.01763429,0.00003567765,0.05616643,0.007650204,0.9077507,0.00016476,0.0000633265,0.0008794605,0.001265728,0.0002003658,0.0008070244,0.00738203],"study_design_scores_gemma":[0.001530366,0.0008349314,0.04386641,0.0005126979,0.9489908,0.0001545408,0.00007865758,0.0013221,0.0004787101,0.0006510879,0.001542506,0.00003721862],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4507666,0.5243892,0.009700071,0.001798926,0.002047767,0.0001650595,0.009043556,0.0002685985,0.001820224],"genre_scores_gemma":[0.9854326,0.01048386,0.001146416,0.0005341556,0.0003012747,0.00007648909,0.001449354,0.00007756117,0.0004982015],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.008821055,"threshold_uncertainty_score":0.04665077,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01972204125380921,"score_gpt":0.2963522604260097,"score_spread":0.2766302191722004,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}