{"id":"W4392501605","doi":"10.1056/nejmc2314021","title":"Actionable Genotypes and Life Span in Iceland","year":2024,"lang":"en","type":"letter","venue":"New England Journal of Medicine","topic":"Health, Environment, Cognitive Aging","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Life span; Span (engineering); Genotype; History; Biology; Evolutionary biology; Genetics; Engineering; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002079048,0.0002663557,0.000786608,0.0004795376,0.001437,0.001223629,0.0004814909,0.008081871,0.002729047],"category_scores_gemma":[0.005305002,0.000193434,0.0003869673,0.0006731203,0.001125238,0.0009555234,0.000681055,0.006623796,0.0006112666],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001552427,"about_ca_system_score_gemma":0.001499726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.05225754,"about_ca_topic_score_gemma":0.08317353,"domain_scores_codex":[0.9995815,0.0001602647,0.0000656068,0.00006225535,0.00005977101,0.00007049573],"domain_scores_gemma":[0.9979809,0.001146602,0.0001889408,0.00007064847,0.0002477169,0.0003652401],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"observational","study_design_scores_codex":[0.001664035,0.000270241,0.1527274,0.0003161245,0.0002324808,0.01074578,0.001795239,0.0005203541,0.000960606,0.007370277,0.736432,0.08696543],"study_design_scores_gemma":[0.0006784059,0.0006623728,0.3536838,0.001752181,0.0005476453,0.006990189,0.006051102,0.0020821,0.0006708147,0.02908699,0.5976122,0.0001821496],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.04573761,0.01380312,0.0003146308,0.9082003,0.01923342,0.0000227673,0.001192191,0.00003576119,0.01146025],"genre_scores_gemma":[0.2410143,0.01383574,0.0007230478,0.6668717,0.05805619,0.0001306195,0.0006477842,0.00004095493,0.01867967],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05225754,"threshold_uncertainty_score":0.1039068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698474328273774,"score_gpt":0.2552102589705271,"score_spread":0.2382255156877894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}