{"id":"W4392501605","doi":"10.1056/nejmc2314021","title":"Actionable Genotypes and Life Span in Iceland","year":2024,"lang":"en","type":"letter","venue":"New England Journal of Medicine","topic":"Health, Environment, Cognitive Aging","field":"Environmental Science","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Life span; Span (engineering); Genotype; History; Biology; Evolutionary biology; Genetics; Engineering; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.001254704,0.0002189189,0.000458103,0.0002099421,0.00004302432,0.00001856649,0.0001573442,0.000237574,0.00238326],"category_scores_gemma":[0.0002881108,0.0001533085,0.000036891,0.0001504025,0.0001803174,0.0001409253,0.00007695935,0.002210371,0.0001073478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002229298,"about_ca_system_score_gemma":0.00008080308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001076181,"about_ca_topic_score_gemma":0.0001989575,"domain_scores_codex":[0.99805,0.0001573764,0.0005289496,0.0003030174,0.0006530437,0.0003076227],"domain_scores_gemma":[0.9989984,0.0003174758,0.0002746999,0.0001418413,0.000007398809,0.0002601833],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004422522,0.0000105198,0.008359078,0.00009536333,0.00003941188,0.002297,0.0009301335,0.00007703533,0.0001708009,0.000001185129,0.9364774,0.0514979],"study_design_scores_gemma":[0.004812049,0.0002540473,0.02467414,0.0004785156,0.00009563709,0.0005325498,0.00006203591,0.00003642962,0.000008508013,0.0008658028,0.9680391,0.0001412116],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.08651304,0.003848756,0.0002027544,0.9014797,0.0009837599,0.0001995932,0.000004878744,0.000009770463,0.006757716],"genre_scores_gemma":[0.1611554,0.008768412,0.000612735,0.783764,0.03563211,0.000005202157,0.00003012583,0.0001168686,0.009915141],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1177157,"threshold_uncertainty_score":0.9985287,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01698474328273774,"score_gpt":0.2552102589705271,"score_spread":0.2382255156877894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}