{"id":"W4392504797","doi":"10.1038/s41586-024-07142-4","title":"The hyphal-specific toxin candidalysin promotes fungal gut commensalism","year":2024,"lang":"en","type":"article","venue":"Nature","topic":"Probiotics and Fermented Foods","field":"Agricultural and Biological Sciences","cited_by":106,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of Allergy and Infectious Diseases; Deutsche Forschungsgemeinschaft; Canadian Institute for Advanced Research; National Institutes of Health; National Science Foundation","keywords":"Hypha; Biology; Commensalism; Microbiology; Candida albicans; Yeast; Colonization; Bacteria; Fungus; Corpus albicans; Multicellular organism; Gastrointestinal tract; Cell; Genetics; Botany; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117271,0.0001100936,0.00008473254,0.000006975545,0.0003193361,0.0003097025,0.0002666514,0.0004534048,0.0001198325],"category_scores_gemma":[0.00001562217,0.00002887447,0.00008733121,0.0003092954,0.00005103615,0.00005010022,0.00006329607,0.001108021,0.00005030923],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002462261,"about_ca_system_score_gemma":0.000006440232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001861254,"about_ca_topic_score_gemma":0.0001865622,"domain_scores_codex":[0.9992169,0.00004046,0.0001115212,0.0002180518,0.0001746331,0.0002384638],"domain_scores_gemma":[0.9996633,0.0001654993,0.00001975818,0.00006328017,0.00003312454,0.00005505848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004031576,0.00009302719,0.0003670863,0.00001557231,0.00009479175,0.00007510845,0.0002046758,7.790169e-7,0.3960023,0.05032083,0.2113459,0.3414396],"study_design_scores_gemma":[0.00004683568,0.00009869596,0.008422732,0.00002863681,0.000009915178,0.00001910434,0.00008537567,0.0001385079,0.003628706,0.003063767,0.9843263,0.0001314343],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8749482,0.04132837,0.000002336336,0.07202625,0.001874285,0.0003731827,0.0002064957,0.0002784209,0.008962433],"genre_scores_gemma":[0.9968413,0.0003026304,0.00002107878,0.0006431117,0.0005135254,0.000006267513,0.0000467141,0.000001124288,0.001624233],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7729804,"threshold_uncertainty_score":0.481386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01025904217036013,"score_gpt":0.2283981470109714,"score_spread":0.2181391048406113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}