{"id":"W4392506974","doi":"10.1016/bs.acc.2024.02.004","title":"Advances in familial hypercholesterolemia","year":2024,"lang":"en","type":"article","venue":"Advances in clinical chemistry","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Montreal Clinical Research Institute","funders":"","keywords":"Familial hypercholesterolemia; Guideline; Medicine; Risk stratification; Atherosclerotic cardiovascular disease; Disease; Intensive care medicine; Clinical trial; Precision medicine; Internal medicine; Pathology; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00214201,0.0005686957,0.0006897874,0.001799063,0.0003217609,0.001375684,0.0003557086,0.001165245,0.003291599],"category_scores_gemma":[0.002907165,0.0001983765,0.0003977567,0.001091129,0.0007155819,0.001279218,0.00067289,0.001940434,0.0009736736],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001172159,"about_ca_system_score_gemma":0.001850669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002811325,"about_ca_topic_score_gemma":0.003420314,"domain_scores_codex":[0.9994585,0.0001479103,0.0001010598,0.00007897398,0.0001500845,0.00006344158],"domain_scores_gemma":[0.9977962,0.0008751249,0.0002378799,0.0001174844,0.0006769713,0.0002964407],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008686932,0.0003506629,0.007791919,0.002742429,0.0001953687,0.001009076,0.0003088707,0.0003295259,0.007602282,0.01960024,0.03913385,0.9200671],"study_design_scores_gemma":[0.0002332406,0.0006657448,0.02361462,0.002230835,0.0004178762,0.003569679,0.0003272919,0.0007414648,0.003968469,0.01501978,0.9491529,0.00005799365],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.009415427,0.9495503,0.001796849,0.02737665,0.002684735,0.00000972815,0.0001019345,0.00008266673,0.008981646],"genre_scores_gemma":[0.07243107,0.899848,0.004425046,0.006463633,0.01188657,0.00002111082,0.0001865969,0.00002280511,0.004715225],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003291599,"threshold_uncertainty_score":0.01132816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02398084689320888,"score_gpt":0.3991943561336079,"score_spread":0.375213509240399,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}