{"id":"W4392541987","doi":"10.1093/schbul/sbae011","title":"Accelerating Medicines Partnership® Schizophrenia (AMP® SCZ): Rationale and Study Design of the Largest Global Prospective Cohort Study of Clinical High Risk for Psychosis","year":2024,"lang":"en","type":"article","venue":"Schizophrenia Bulletin","topic":"Schizophrenia research and treatment","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas College; École de Technologie Supérieure; University of Calgary","funders":"Cilag; Instituto de Salud Carlos III; National Health and Medical Research Council; H. Lundbeck A/S; Servier; Ministerio de Ciencia e Innovación; National Institute for Health and Care Research; Wellcome Trust; Medical Research Council; Biogen; Gedeon Richter; Neurocrine Biosciences; Sunovion; Takeda Pharmaceuticals U.S.A.; National Institute of Mental Health; Pfizer; Bristol-Myers Squibb; Eli Lilly and Company; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Schizophrenia (object-oriented programming); Psychosis; Psychiatry; Prospective cohort study; Medicine; General partnership; Cohort study; Internal medicine; Political science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05309989,0.001368868,0.001130102,0.002301503,0.003150379,0.00155011,0.002586553,0.001456437,0.004026071],"category_scores_gemma":[0.05009562,0.00147816,0.001537667,0.003063134,0.002083053,0.001157494,0.007274624,0.002097193,0.001443442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001467694,"about_ca_system_score_gemma":0.009800025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.009358608,"about_ca_topic_score_gemma":0.01603584,"domain_scores_codex":[0.9649549,0.02811176,0.001715338,0.002031644,0.002428946,0.0007573811],"domain_scores_gemma":[0.9866,0.00465367,0.001474661,0.003354276,0.002382136,0.001535377],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02470979,0.002414854,0.6223928,0.003522769,0.001868658,0.001930635,0.01135531,0.005144218,0.004408184,0.0552744,0.06883341,0.198145],"study_design_scores_gemma":[0.0224756,0.01499836,0.5915481,0.004088653,0.002733641,0.003080787,0.006274671,0.009723838,0.003569388,0.05324544,0.287825,0.0004364825],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"protocol","genre_gemma":"methods","genre_scores_codex":[0.2177656,0.004770839,0.1907244,0.013886,0.001691065,0.4868314,0.05892599,0.0007408807,0.02466384],"genre_scores_gemma":[0.1710066,0.001120493,0.1902799,0.003849408,0.0004194425,0.621814,0.009093617,0.0001135206,0.002303019],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.05309989,"threshold_uncertainty_score":0.2808224,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06280388264805264,"score_gpt":0.3761419633194906,"score_spread":0.313338080671438,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}