{"id":"W4392544811","doi":"10.21203/rs.3.rs-3997065/v1","title":"Consistent Cord Blood DNA Methylation Signatures of Gestational Age between South Asian and white European Cohorts","year":2024,"lang":"en","type":"preprint","venue":"Research Square","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Children's Hospital Research Institute of Manitoba; Hospital for Sick Children; St. Joseph’s Healthcare Hamilton; University of British Columbia; University of Toronto; SickKids Foundation; University of Alberta; Population Health Research Institute; McMaster University","funders":"Canadian Institutes of Health Research; Partenariat Canadien Contre Le Cancer; Children's Health Research Institute; Heart and Stroke Foundation of Canada","keywords":"Cord blood; DNA methylation; White (mutation); Gestational age; Methylation; Obstetrics; Medicine; Demography; Biology; Genetics; Pregnancy; DNA; Gene; Sociology; Gene expression","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009559213,0.0002684347,0.0002982498,0.0005696858,0.0005548246,0.0007401265,0.0003893999,0.0002508567,0.002014294],"category_scores_gemma":[0.002280392,0.0001890419,0.0004813025,0.0009789156,0.0004193474,0.000198283,0.0007845362,0.0002681848,0.0001695265],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003370331,"about_ca_system_score_gemma":0.0006444723,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03419728,"about_ca_topic_score_gemma":0.05044043,"domain_scores_codex":[0.9993265,0.00009737864,0.00006491259,0.0003277987,0.00008793912,0.0000955049],"domain_scores_gemma":[0.9990181,0.0001602366,0.000288139,0.0001935371,0.0001946466,0.0001454439],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004218668,0.00001089456,0.9853994,0.00005529254,0.000462762,0.0001514562,0.0008480434,0.00007687914,0.007549549,0.0002654204,0.0002622894,0.004496136],"study_design_scores_gemma":[0.00000909226,0.00003651504,0.9976307,0.00001924892,0.0001536297,0.0002032408,0.0003891648,0.0001323877,0.0006823184,0.0001136913,0.0006234132,0.000006488521],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974578,0.0003918997,0.0004895272,0.00005458303,0.00001184973,0.000007955622,0.0008726084,0.000008072994,0.0007055326],"genre_scores_gemma":[0.9986446,0.0001588223,0.0002556976,0.00004351029,0.000004949089,0.00001076937,0.0005880584,0.000007537089,0.0002859725],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03419728,"threshold_uncertainty_score":0.06799644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04705022873990047,"score_gpt":0.3573354846873797,"score_spread":0.3102852559474792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}