{"id":"W4392557907","doi":"10.1186/s13063-024-07982-5","title":"IA-PACS-CFS: a double-blinded, randomized, sham-controlled, exploratory trial of immunoadsorption in patients with chronic fatigue syndrome (CFS) including patients with post-acute COVID-19 CFS (PACS-CFS)","year":2024,"lang":"en","type":"article","venue":"Trials","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Charité – Universitätsmedizin Berlin; Bundesministerium für Bildung und Forschung","keywords":"Medicine; Chronic fatigue syndrome; Randomized controlled trial; Internal medicine; Immunoadsorption; Tolerability; Placebo; myalgia; Immunology; Adverse effect; Antibody; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.008229913,0.0009242422,0.005275931,0.001723703,0.0002174466,0.0002146395,0.0005051253,0.0005328245,0.0009111386],"category_scores_gemma":[0.002642383,0.0006096777,0.0008728685,0.001648788,0.0005740945,0.0008546118,0.0001978385,0.001026865,0.0001092228],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002205007,"about_ca_system_score_gemma":0.004469851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006667241,"about_ca_topic_score_gemma":0.0000586895,"domain_scores_codex":[0.9894414,0.002126289,0.003309291,0.00124848,0.002652093,0.001222456],"domain_scores_gemma":[0.9936445,0.002732772,0.001158538,0.001138966,0.0007194209,0.0006057962],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9846196,0.00159448,0.002998302,0.003536306,0.00376725,0.0002744942,0.00131648,0.0001289424,0.0006381196,0.0002024002,0.0003343305,0.000589278],"study_design_scores_gemma":[0.9763733,0.01269978,0.002507557,0.004859031,0.001738891,0.00004596571,0.0002492336,0.0002032682,0.0004568119,0.00008639389,0.00008935305,0.0006904169],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9726593,0.00240336,0.0003469571,0.0007686246,0.0009063063,0.02228495,0.0002458382,0.0002229767,0.000161716],"genre_scores_gemma":[0.9954481,0.0003202462,0.0001546,0.00004596902,0.0001924151,0.002459418,0.0008825678,0.0001900721,0.0003066121],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02278883,"threshold_uncertainty_score":0.9996355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0937607569442525,"score_gpt":0.3898748511397702,"score_spread":0.2961140941955177,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}