{"id":"W4392558483","doi":"10.3389/fimmu.2024.1317522","title":"A novel type-2 innate lymphoid cell-based immunotherapy for cancer","year":2024,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"","keywords":"Innate lymphoid cell; Immunotherapy; Adoptive cell transfer; CD8; Immunology; Medicine; Immune system; Cancer immunotherapy; Cancer research; Cancer; Tumor-infiltrating lymphocytes; T cell; Innate immune system; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001139266,0.0003377613,0.0002316785,0.0002459504,0.0001627873,0.0003456748,0.0002473088,0.0004404545,0.001613203],"category_scores_gemma":[0.00004860539,0.00008781806,0.0003081388,0.0001380169,0.0001795684,0.0002767251,0.0002566847,0.0006980593,0.0004789821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000166673,"about_ca_system_score_gemma":0.0003070667,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001304637,"about_ca_topic_score_gemma":0.0003121533,"domain_scores_codex":[0.9998993,0.00001843527,0.000004298075,0.00002444975,0.00003160399,0.00002194504],"domain_scores_gemma":[0.9999804,0.00000200178,0.000003705013,0.000003214214,0.000003135845,0.000007561182],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001342289,0.0001314813,0.0002437867,0.0001827985,0.000009916147,0.0001584906,0.00002166716,0.0002662384,0.9810895,0.001327829,0.0008474494,0.01558646],"study_design_scores_gemma":[0.0003366691,0.004101014,0.005762708,0.00007577454,0.0001111602,0.003995636,0.00005768176,0.007335458,0.7984086,0.001716313,0.1780544,0.00004453048],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8253345,0.05969175,0.0835286,0.002927646,0.001263075,0.0008848227,0.001331174,0.001041488,0.02399703],"genre_scores_gemma":[0.934278,0.01565188,0.02903536,0.001574312,0.0002790233,0.0005667324,0.0009797382,0.00004291266,0.01759202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001613203,"threshold_uncertainty_score":0.005396664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01150285770143173,"score_gpt":0.2422052160139359,"score_spread":0.2307023583125042,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}