{"id":"W4392578473","doi":"10.1016/j.heliyon.2024.e27429","title":"Atrophy of hippocampal subfields and amygdala nuclei in subjects with mild cognitive impairment progressing to Alzheimer's disease","year":2024,"lang":"en","type":"article","venue":"Heliyon","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; Northern California Institute for Research and Education; Ministero della Salute; Pfizer; Novartis Pharmaceuticals Corporation; University of Southern California; Associazione Italiana Ricerca Alzheimer; Biogen; Eli Lilly and Company; Bristol-Myers Squibb; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; Alzheimer's Association","keywords":"Subiculum; Amygdala; Atrophy; Hippocampal formation; Psychology; Hippocampus; Magnetic resonance imaging; Neuroscience; Alzheimer's disease; Internal medicine; Medicine; Pathology; Disease; Radiology; Dentate gyrus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001994954,0.0001676703,0.0002363785,0.0003178238,0.00003951338,0.00005882797,0.00004297902,0.00004763429,0.0001178498],"category_scores_gemma":[0.00003063746,0.0001273455,0.00005396897,0.0004389962,0.0001206243,0.0001027711,0.00007151618,0.0002042169,0.0000270268],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003737697,"about_ca_system_score_gemma":0.0001998099,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002359518,"about_ca_topic_score_gemma":0.00002333856,"domain_scores_codex":[0.9985673,0.00006242435,0.0002017981,0.0003711387,0.00043841,0.0003589031],"domain_scores_gemma":[0.9993155,0.00007981649,0.00002525256,0.0001184218,0.0001162362,0.000344753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.005658305,0.0007563242,0.9352671,0.002609618,0.0003233213,0.001879367,0.002159461,0.000001247312,0.001564139,0.00008114326,0.00009460868,0.04960538],"study_design_scores_gemma":[0.00246844,0.003252581,0.9748595,0.008563225,0.0003910546,0.00003283101,0.0009763431,0.0001290092,0.008924252,0.00004525919,0.0001604017,0.0001971011],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867031,0.009963715,0.00006409554,0.0009115918,0.00004928458,0.00121538,0.00001867752,0.00004679515,0.001027359],"genre_scores_gemma":[0.9988289,0.0003286383,0.0002239715,0.0002653166,0.00007266545,0.0001214175,0.00001939721,0.00002912717,0.0001105592],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04940828,"threshold_uncertainty_score":0.5193,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01811345308097262,"score_gpt":0.3167800524220912,"score_spread":0.2986665993411186,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}