{"id":"W4392589427","doi":"10.1016/j.gimo.2024.101649","title":"P745: High-fidelity whole genome sequencing of FFPE tumor-derived nucleic acids stored at ambient temperature","year":2024,"lang":"en","type":"article","venue":"Genetics in Medicine Open","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University Health Network","funders":"","keywords":"Nucleic acid; Genome; Computational biology; Fidelity; Biology; Genetics; Computer science; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005388891,0.0002493313,0.0004098648,0.0001005451,0.00007120155,0.00005590179,0.0006498709,0.0001665035,0.0001318399],"category_scores_gemma":[0.0001521759,0.0002279353,0.00006613886,0.0002402722,0.0002096082,0.000005396996,0.0008678876,0.0002078003,0.00001513506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002182352,"about_ca_system_score_gemma":0.0003621212,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005856931,"about_ca_topic_score_gemma":0.001012436,"domain_scores_codex":[0.9981876,0.00007028392,0.0005362202,0.0006256122,0.0002439785,0.0003363023],"domain_scores_gemma":[0.9989049,0.00003861288,0.000106074,0.0006787668,0.0001285665,0.000143024],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008251411,0.00002708081,0.001289364,0.0001017079,0.0000531737,0.00004969948,0.0004253615,0.001303758,0.9921191,0.00008666771,0.004035685,0.0004258578],"study_design_scores_gemma":[0.003071511,0.001619908,0.03821661,0.0006168886,0.0001478228,0.0000699228,0.001012761,0.0006130181,0.7938914,0.001133871,0.158816,0.0007902738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9864362,0.01054455,0.0001082658,0.0006604119,0.0007027754,0.0005440642,0.0001964394,0.00001035898,0.0007968718],"genre_scores_gemma":[0.9938421,0.002036152,0.001631671,0.0008233016,0.0005422204,0.00004110157,0.0004676075,0.00005393146,0.0005619145],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1982278,"threshold_uncertainty_score":0.9294932,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01786925219478167,"score_gpt":0.2855487617342628,"score_spread":0.2676795095394812,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}