{"id":"W4392589457","doi":"10.1016/j.gimo.2024.101373","title":"P474: Precision child health: Integrating a consultative pharmacogenetics (PGx) program into clinical care at the Hospital for Sick Children*","year":2024,"lang":"en","type":"article","venue":"Genetics in Medicine Open","topic":"Pharmaceutical studies and practices","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"Sick child; Pharmacogenetics; Medicine; Health care; Pediatrics; Genetics; Genotype; Political science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002270039,0.0003107927,0.0007151482,0.00007115174,0.0004228738,0.0001024385,0.0005093337,0.0001184789,0.0001751736],"category_scores_gemma":[0.001641518,0.0001796417,0.0001316286,0.0004550132,0.0005634833,0.00006634759,0.0007298956,0.000915904,0.00002831826],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002183243,"about_ca_system_score_gemma":0.0002742676,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00028764,"about_ca_topic_score_gemma":0.0003913159,"domain_scores_codex":[0.997018,0.0003248407,0.001013481,0.0006919935,0.0004576573,0.0004939859],"domain_scores_gemma":[0.9968865,0.002000235,0.0002058435,0.0003515769,0.0002502661,0.0003055929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0005296994,0.0002915556,0.01295314,0.000337897,0.0003578262,0.00002531693,0.01277295,0.00001586998,0.00003605548,0.0001049674,0.03487884,0.9376959],"study_design_scores_gemma":[0.008734483,0.009718026,0.01938491,0.002647371,0.0007207833,0.00008733362,0.00976873,0.007168841,0.0005454372,0.0004985514,0.9403128,0.0004127191],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4566313,0.2950458,0.0008411016,0.2055842,0.004111984,0.02420769,0.0001677489,0.0001818774,0.01322831],"genre_scores_gemma":[0.9211668,0.04394617,0.02042026,0.009567728,0.002747619,0.001182457,0.0003551776,0.0001090339,0.000504721],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9372832,"threshold_uncertainty_score":0.7325578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1193006552684117,"score_gpt":0.5519946523825524,"score_spread":0.4326939971141407,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}