{"id":"W4392599830","doi":"10.1186/s40635-024-00609-8","title":"Impact of age on the host response to sepsis in a murine model of fecal-induced peritonitis","year":2024,"lang":"en","type":"article","venue":"Intensive Care Medicine Experimental","topic":"Sepsis Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Manitoba; McMaster University; Ottawa Hospital; Thrombosis and Atherosclerosis Research Institute","funders":"Institute of Circulatory and Respiratory Health; McMaster University","keywords":"Medicine; Peritonitis; Feces; Sepsis; Host (biology); Host response; Intensive care medicine; Immunology; Internal medicine; Microbiology; Immune system; Biology; Ecology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004398406,0.0007485988,0.0005032283,0.0004554653,0.0001662138,0.0003420138,0.0002484825,0.0004936848,0.001181558],"category_scores_gemma":[0.0001484,0.0001920611,0.0004907318,0.0002005681,0.0003569063,0.0004444318,0.0002717996,0.001106199,0.000259447],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002865239,"about_ca_system_score_gemma":0.0002742483,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002726179,"about_ca_topic_score_gemma":0.0005362892,"domain_scores_codex":[0.9997376,0.00004781569,0.00002542009,0.00005583854,0.00006267082,0.00007066283],"domain_scores_gemma":[0.9996182,0.00002103819,0.0001745444,0.00003385644,0.00003107399,0.0001212119],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004152788,0.0008614078,0.002551819,0.000141978,0.00002401932,0.0002128748,0.00005848343,0.0002068129,0.9876035,0.00008920312,0.0001327635,0.003964444],"study_design_scores_gemma":[0.0003627404,0.05375246,0.08603993,0.0001229742,0.0002372788,0.001376631,0.0002036172,0.002210153,0.8510287,0.000260261,0.004355446,0.0000497086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955363,0.001786439,0.001136966,0.0001388018,0.00006928105,0.00007191987,0.0005749914,0.00005046541,0.0006347962],"genre_scores_gemma":[0.9928392,0.001959458,0.002286329,0.0001913724,0.00005311416,0.0001792405,0.0006315318,0.00001707752,0.001842712],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001181558,"threshold_uncertainty_score":0.003952742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1099783661885093,"score_gpt":0.4232376743260104,"score_spread":0.3132593081375011,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}