{"id":"W4392603197","doi":"10.1016/j.mce.2024.112196","title":"Autophagy inhibition suppresses hormone production and cell growth in pituitary tumor cells: A potential approach to pituitary tumors","year":2024,"lang":"en","type":"article","venue":"Molecular and Cellular Endocrinology","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Japan Society for the Promotion of Science; University of Alberta","keywords":"Autophagy; Cell growth; Cancer research; Cell culture; Biology; Pituitary tumors; Apoptosis; Internal medicine; Cell biology; Endocrinology; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001589653,0.0004134647,0.000482864,0.0003776617,0.0003892154,0.000516606,0.0002761126,0.000321992,0.001585056],"category_scores_gemma":[0.00007526765,0.0001289144,0.0005273972,0.0003145795,0.0003152923,0.0002728852,0.0002342312,0.000951498,0.0003062413],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004361036,"about_ca_system_score_gemma":0.0006562361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006431264,"about_ca_topic_score_gemma":0.002213812,"domain_scores_codex":[0.9999177,0.00001206501,0.000007399355,0.00001453916,0.00001782246,0.00003037435],"domain_scores_gemma":[0.9999551,0.000006652751,0.000009739962,0.000006250338,0.000007375916,0.00001489479],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002129459,0.0003131867,0.0008355072,0.000439589,0.00007372231,0.0003315059,0.00005715865,0.0002743074,0.969855,0.001316155,0.001463391,0.02291115],"study_design_scores_gemma":[0.0005174007,0.002957257,0.01066589,0.00004797449,0.0002425589,0.001550001,0.0002410473,0.001149528,0.9369431,0.001057326,0.04458642,0.00004154203],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.935429,0.04334246,0.005556275,0.002410798,0.0006975142,0.0001441321,0.001525221,0.0006206802,0.01027404],"genre_scores_gemma":[0.9792356,0.01276612,0.002505637,0.0003817766,0.00009202839,0.00007458594,0.0009225444,0.00003998398,0.003981832],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001585056,"threshold_uncertainty_score":0.005302548,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005816750631646397,"score_gpt":0.2057026405576316,"score_spread":0.1998858899259852,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}