{"id":"W4392613097","doi":"10.1016/j.jtct.2024.03.006","title":"Gut Immunomodulation with Vedolizumab prior to Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Patients with Inflammatory Bowel Disease","year":2024,"lang":"en","type":"article","venue":"Transplantation and Cellular Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"","keywords":"Vedolizumab; Hematopoietic stem cell transplantation; Medicine; Inflammatory bowel disease; Transplantation; Stem cell; Immunology; Disease; Haematopoiesis; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001780275,0.0003663526,0.0002985082,0.0004771572,0.00009272428,0.00008192413,0.00007816122,0.0001140261,0.00004591142],"category_scores_gemma":[5.698727e-7,0.0002871719,0.00006397012,0.0004442483,0.00004376973,0.0002660704,0.000002318732,0.0001979308,0.00003965829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007134436,"about_ca_system_score_gemma":0.0001891751,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001047838,"about_ca_topic_score_gemma":0.00002412533,"domain_scores_codex":[0.9979466,0.0001019467,0.000489345,0.0005776038,0.0005495314,0.0003349815],"domain_scores_gemma":[0.99924,0.00008495431,0.00007090805,0.0002370931,0.00008485022,0.0002821511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02330605,0.0009072107,0.8712651,0.01738832,0.0001988801,0.002337008,0.03833717,0.001826702,0.02797753,0.0004605726,0.00001112609,0.01598434],"study_design_scores_gemma":[0.009380703,0.000748529,0.9764714,0.0009773872,0.0005091093,0.0000740469,0.0001902772,0.0003496787,0.01068659,0.00002799404,0.00007605729,0.0005082216],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823425,0.001548977,0.01356969,0.0001696881,0.00009321232,0.001874403,0.00005560465,0.0001545895,0.0001913681],"genre_scores_gemma":[0.9951541,0.003206164,0.0004228407,0.0001399748,0.00005091257,0.0001576148,0.0006604764,0.00008611069,0.0001217705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1052063,"threshold_uncertainty_score":0.999958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007515011372400853,"score_gpt":0.2153247245900678,"score_spread":0.2078097132176669,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}