{"id":"W4392623780","doi":"10.1007/s12016-024-08984-6","title":"B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases","year":2024,"lang":"en","type":"article","venue":"Clinical Reviews in Allergy & Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; Chinese Academy of Medical Sciences; National Natural Science Foundation of China","keywords":"Immunology; breakpoint cluster region; Pathogenesis; Repertoire; Autoimmune disease; B-cell receptor; Biology; Immune system; Disease; B cell; Autoimmunity; Medicine; Receptor; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity","insufficient_payload"],"consensus_categories":["research_integrity","insufficient_payload"],"category_scores_codex":[0.00205017,0.0006992253,0.002215054,0.0005066594,0.0001511023,0.00003799857,0.001191706,0.00132114,0.00530829],"category_scores_gemma":[0.001688852,0.000573797,0.0006742522,0.001031906,0.001383888,0.0003548576,0.0005695213,0.002582709,0.009833951],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002465991,"about_ca_system_score_gemma":0.0003399938,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007074789,"about_ca_topic_score_gemma":0.0001802925,"domain_scores_codex":[0.9903989,0.003069663,0.003554228,0.001598587,0.00007347867,0.001305187],"domain_scores_gemma":[0.9961541,0.001918145,0.0004412793,0.001343838,0.00007860054,0.00006397789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00081838,0.002497284,0.001823889,0.0002494094,0.0003473983,0.0002091498,0.0002426612,0.000007059499,0.2283673,0.00377308,0.02500489,0.7366595],"study_design_scores_gemma":[0.002563809,0.0006439196,0.002065493,0.0008278695,0.00003566081,0.00006465224,0.0001012807,0.000008166516,0.002294674,0.0009575051,0.9898399,0.0005970889],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.05701991,0.9242707,0.00003224412,0.002213011,0.01111797,0.0008309987,0.00002336965,0.0002796149,0.00421215],"genre_scores_gemma":[0.104338,0.8837787,0.0001618546,0.0007691634,0.0001291548,0.0003792393,0.0003051202,0.00007598702,0.01006277],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.964835,"threshold_uncertainty_score":0.9999754,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03022678398688717,"score_gpt":0.3284620636187118,"score_spread":0.2982352796318246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}