{"id":"W4392623780","doi":"10.1007/s12016-024-08984-6","title":"B-Cell Receptor Repertoire: Recent Advances in Autoimmune Diseases","year":2024,"lang":"en","type":"article","venue":"Clinical Reviews in Allergy & Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health","funders":"National Key Research and Development Program of China; Chinese Academy of Medical Sciences; National Natural Science Foundation of China","keywords":"Immunology; breakpoint cluster region; Pathogenesis; Repertoire; Autoimmune disease; B-cell receptor; Biology; Immune system; Disease; B cell; Autoimmunity; Medicine; Receptor; Antibody; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001134996,0.0005758308,0.001217656,0.001099752,0.0001645065,0.001282836,0.0005586104,0.0008712881,0.001932583],"category_scores_gemma":[0.001194183,0.0002385272,0.0003037317,0.001250995,0.0005240351,0.001401017,0.0006466475,0.001096031,0.0007598259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004264611,"about_ca_system_score_gemma":0.0004616153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003575888,"about_ca_topic_score_gemma":0.0003958307,"domain_scores_codex":[0.9996686,0.0000795494,0.00004363631,0.00009203529,0.00006769063,0.00004850817],"domain_scores_gemma":[0.9992053,0.0003998759,0.000106585,0.00003139332,0.0001583542,0.00009860112],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001330505,0.0001040898,0.003470524,0.007234,0.0001624946,0.0003130356,0.0001347081,0.000504146,0.04084669,0.002643487,0.009499741,0.9337566],"study_design_scores_gemma":[0.0002153668,0.001541008,0.04168579,0.005376605,0.00125895,0.008537258,0.0004808965,0.001331275,0.01214947,0.01227246,0.9150124,0.0001384495],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.003883529,0.9932756,0.0006360398,0.0009852801,0.0003034302,0.000003515491,0.00004857959,0.00002038173,0.0008436285],"genre_scores_gemma":[0.02477171,0.9697828,0.001349825,0.001244537,0.001969455,0.00001362382,0.0001355969,0.00001008572,0.0007224077],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001932583,"threshold_uncertainty_score":0.006465137,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03022678398688717,"score_gpt":0.3284620636187118,"score_spread":0.2982352796318246,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}