{"id":"W4392663220","doi":"10.1096/fj.202300828rrr","title":"German cockroach extract prevents <scp>IL</scp> ‐13‐induced <scp>CCL26</scp> expression in airway epithelial cells through <scp>IL</scp> ‐13 degradation","year":2024,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Allergic Rhinitis and Sensitization","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Proteases; Downregulation and upregulation; Chemistry; Eosinophil; Cell biology; Serine protease; Immunology; Protease; Biochemistry; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009526018,0.0002902649,0.0002635336,0.0001667184,0.0001160757,0.0002123564,0.0001127597,0.0002120497,0.001162035],"category_scores_gemma":[0.00007693534,0.0001128959,0.0002569748,0.0001079709,0.0001951428,0.0001168719,0.0001395846,0.0005398693,0.0003184134],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001770849,"about_ca_system_score_gemma":0.0002237242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008613269,"about_ca_topic_score_gemma":0.001640495,"domain_scores_codex":[0.9998733,0.00002058139,0.00001278452,0.00002875096,0.00002791154,0.00003666665],"domain_scores_gemma":[0.9999317,0.000009801605,0.00001844343,0.00001009994,0.00001090161,0.00001907831],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000174993,0.00003576235,0.000104724,0.00003396399,0.000003897953,0.00002461758,0.000004677374,0.00001278763,0.9991327,0.000009265662,0.00002661513,0.0004359628],"study_design_scores_gemma":[0.00002428222,0.0005728867,0.01376843,0.00001027127,0.00001858458,0.0001649512,0.00003388207,0.0002923301,0.9833,0.00001421422,0.001796539,0.000003545482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962107,0.00155284,0.0007950883,0.00009391559,0.0000231442,0.00002741322,0.0004138787,0.00005573454,0.0008272698],"genre_scores_gemma":[0.9936196,0.0007957955,0.001238872,0.0001011835,0.00001028435,0.00003609739,0.001148716,0.00001869721,0.003030745],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001162035,"threshold_uncertainty_score":0.003887355,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0266981961038858,"score_gpt":0.2825103457784373,"score_spread":0.2558121496745515,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}