{"id":"W4392703669","doi":"10.1021/acs.jafc.4c00829","title":"Antioxidant and Angiotensin-Converting Enzyme Inhibitory Activity of Faba Bean-Derived Peptides After <i>In Vitro</i> Gastrointestinal Digestion: Insight into Their Mechanism of Action","year":2024,"lang":"en","type":"article","venue":"Journal of Agricultural and Food Chemistry","topic":"Protein Hydrolysis and Bioactive Peptides","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Agriculture and Agri-Food Canada","funders":"","keywords":"IC50; Trolox; Chemistry; Antioxidant; EC50; Nutraceutical; DPPH; ABTS; Biochemistry; Enzyme; In vitro; Mechanism of action; Peptide; Pharmacology; Food science; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001302882,0.0001627741,0.0002585295,0.00003200617,0.00002940444,0.00002308458,0.00005748715,0.00009753436,0.000002361125],"category_scores_gemma":[0.00003236762,0.000100233,0.0001430862,0.00007779182,0.0001019359,0.00003434734,0.00007177677,0.0001838484,5.951122e-8],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001920045,"about_ca_system_score_gemma":0.0000325369,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009341214,"about_ca_topic_score_gemma":0.000005107589,"domain_scores_codex":[0.9992263,0.00002805917,0.0003203881,0.0001856977,0.0001195612,0.0001199907],"domain_scores_gemma":[0.9994453,0.00001972089,0.000260388,0.00006237678,0.0001487856,0.0000634619],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002433294,0.00005783085,0.0003257688,0.0002162136,0.0000839573,0.000006791221,0.0001421725,0.000002604779,0.9974405,0.00000147185,0.00001141533,0.001467902],"study_design_scores_gemma":[0.0002645556,0.0003884651,0.01794874,0.0004319857,0.00003854756,0.0005966508,0.0003058946,0.00001672781,0.9798158,0.0000439178,0.00003006308,0.0001186736],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9956542,0.003943093,0.0001057893,0.0001627746,0.00003706908,0.0000542711,0.00001359663,0.000003428731,0.00002584027],"genre_scores_gemma":[0.9989565,0.0003390157,0.0004380301,0.000008661134,0.0002230515,0.000002283301,0.000005943618,0.00000636668,0.00002015747],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01762476,"threshold_uncertainty_score":0.4087382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007248528709282102,"score_gpt":0.1998892245048313,"score_spread":0.1926406957955492,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}