{"id":"W4392754020","doi":"10.1080/14737140.2024.2330601","title":"Neo-adjuvant therapies for ER positive/HER2 negative breast cancers: from chemotherapy to hormonal therapy, CDK inhibitors, and beyond","year":2024,"lang":"en","type":"review","venue":"Expert Review of Anticancer Therapy","topic":"Breast Cancer Treatment Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"NOSM University; Essar Steel Algoma (Canada); Sault Area Hospital","funders":"","keywords":"Medicine; Oncology; Breast cancer; Adjuvant; Internal medicine; Chemotherapy; Hormonal therapy; Adjuvant therapy; Cancer; Disease","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004669101,0.0004840347,0.0009568325,0.001446241,0.0001613191,0.0006771145,0.0005703261,0.0006867042,0.005216294],"category_scores_gemma":[0.0008983994,0.0001550408,0.0006010609,0.001352043,0.0002961761,0.0007821856,0.0003812895,0.00140149,0.001882065],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005475082,"about_ca_system_score_gemma":0.0008294137,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009078321,"about_ca_topic_score_gemma":0.002360805,"domain_scores_codex":[0.9998123,0.0000448589,0.00002734567,0.00003217861,0.00006657917,0.00001678526],"domain_scores_gemma":[0.9996137,0.000206478,0.00006535101,0.000007560327,0.00008766609,0.0000192326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008050349,0.00003572058,0.0001065082,0.02724148,0.00009520421,0.0000900341,0.00003542936,0.0002452918,0.0009055667,0.002049241,0.0434483,0.9256667],"study_design_scores_gemma":[0.00003701638,0.0001213132,0.0008787198,0.01492983,0.0001922111,0.001039319,0.0000557262,0.00008564995,0.000351907,0.00188597,0.9804068,0.00001547843],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006944043,0.9985321,0.00005377282,0.0004240243,0.0001698685,0.000004562907,0.0000229822,0.000004653053,0.0007186694],"genre_scores_gemma":[0.0005020428,0.9984642,0.00009011541,0.0003369632,0.000133164,0.000005068728,0.00003074856,0.000001192886,0.0004364082],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005216294,"threshold_uncertainty_score":0.01745027,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01901794872321056,"score_gpt":0.3459930498305318,"score_spread":0.3269751011073212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}