{"id":"W4392756186","doi":"10.3389/fimmu.2024.1272351","title":"Recent progress in combination therapy of oncolytic vaccinia virus","year":2024,"lang":"en","type":"article","venue":"Frontiers in Immunology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier Universitaire de Sherbrooke; Université de Sherbrooke; Ottawa Hospital; University of British Columbia","funders":"","keywords":"Oncolytic virus; Vaccinia; Virus; Immunotherapy; Medicine; Virotherapy; Virology; Immune system; Biology; Immunology; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001601586,0.0007510164,0.001639076,0.001256035,0.0003123623,0.001172482,0.0008121874,0.0006514789,0.001391175],"category_scores_gemma":[0.0006246819,0.0004271914,0.0009096265,0.001046842,0.0003839683,0.001143682,0.0008099612,0.001613767,0.0006161301],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007528429,"about_ca_system_score_gemma":0.0005526851,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005322673,"about_ca_topic_score_gemma":0.0005640634,"domain_scores_codex":[0.9992919,0.0001673824,0.00005869235,0.0002034156,0.0002036693,0.00007482001],"domain_scores_gemma":[0.9997059,0.0001009616,0.0000521103,0.00003762334,0.00006190459,0.00004164143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001808606,0.001139334,0.002653579,0.005286775,0.0006727524,0.0004832658,0.0003114635,0.003234772,0.189483,0.004889773,0.007122086,0.7829146],"study_design_scores_gemma":[0.0006831062,0.01001172,0.006207484,0.0007063689,0.001703571,0.005769867,0.0001245848,0.009745434,0.2966151,0.002721606,0.6655431,0.0001681627],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06755579,0.9003412,0.02402755,0.0007313904,0.0005991564,0.0002207619,0.0001643554,0.0001942407,0.006165613],"genre_scores_gemma":[0.2940568,0.658289,0.03617666,0.001042519,0.001200257,0.000599538,0.001233795,0.000178616,0.007222869],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001639076,"threshold_uncertainty_score":0.008470118,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01318099155380094,"score_gpt":0.3011126898931072,"score_spread":0.2879316983393063,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}