{"id":"W4392776487","doi":"10.1007/978-1-0716-3730-2_1","title":"Cancer Stem Cells: Current Challenges and Future Perspectives","year":2024,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Cancer Cells and Metastasis","field":"Medicine","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"","keywords":"CRISPR; Epigenome; Stem cell; Precision medicine; Computational biology; Biology; Cancer; Cancer stem cell; Genome editing; Bioinformatics; Medicine; Cancer research; Genetics; Gene; DNA methylation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01728794,0.0008898587,0.00291589,0.001723367,0.001887999,0.009780116,0.00286983,0.005931246,0.01392294],"category_scores_gemma":[0.007270755,0.0005785173,0.001005109,0.001514585,0.008362478,0.0162153,0.004025408,0.009023357,0.003675201],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002256259,"about_ca_system_score_gemma":0.006936299,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001184158,"about_ca_topic_score_gemma":0.004088339,"domain_scores_codex":[0.997849,0.0008134575,0.0002077778,0.0002733674,0.0004721501,0.0003843205],"domain_scores_gemma":[0.988259,0.007062369,0.0004574912,0.0003348108,0.002288222,0.001598162],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001121724,0.0004547022,0.001943688,0.007593121,0.0001181809,0.0006218522,0.001179282,0.001442291,0.005485208,0.1779626,0.1169649,0.6851125],"study_design_scores_gemma":[0.0001519555,0.0007181349,0.00129908,0.004154211,0.0001542328,0.001306945,0.005019241,0.001730338,0.002727781,0.1926216,0.79001,0.0001064564],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002508196,0.8941421,0.005039891,0.09163173,0.002477858,0.00003028533,0.0001374044,0.00009062413,0.003941903],"genre_scores_gemma":[0.03863243,0.9213609,0.009583323,0.01694391,0.009467131,0.0002359696,0.0003666379,0.00005663858,0.00335308],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01728794,"threshold_uncertainty_score":0.09142846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05081577784603496,"score_gpt":0.4421028928892208,"score_spread":0.3912871150431858,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}