{"id":"W4392788581","doi":"10.1111/bjh.19314","title":"Venetoclax resistance in acute myeloid leukaemia—Clinical and biological insights","year":2024,"lang":"en","type":"article","venue":"British Journal of Haematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Venetoclax; Medicine; Myeloid leukemia; Clinical trial; Oncology; Immunology; Internal medicine; Leukemia; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004542438,0.0001866444,0.0003501895,0.0005625534,0.00009567267,0.0005548471,0.0002621926,0.0003927441,0.001356921],"category_scores_gemma":[0.0003196135,0.00007974583,0.000185841,0.0005116977,0.0001948468,0.0004784901,0.0002145988,0.0007456938,0.0003639884],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000255672,"about_ca_system_score_gemma":0.0002738073,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002218435,"about_ca_topic_score_gemma":0.000503701,"domain_scores_codex":[0.9999143,0.00002413719,0.00001067206,0.0000132339,0.00002434226,0.00001331015],"domain_scores_gemma":[0.9998807,0.00004942682,0.00002638771,0.000005372319,0.00002451491,0.00001361709],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0005950533,0.0002267532,0.002632459,0.005720978,0.00007264746,0.001170009,0.0001393898,0.0005605784,0.02166671,0.00560409,0.009015078,0.9525963],"study_design_scores_gemma":[0.0003531388,0.003730237,0.019827,0.002838204,0.0004308169,0.02371752,0.0002226756,0.001370821,0.01511388,0.01015022,0.9221918,0.00005359362],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005811398,0.9908501,0.0002851862,0.0008944398,0.0001029659,0.00001023931,0.00003310188,0.00001131451,0.002001302],"genre_scores_gemma":[0.05849414,0.9377538,0.000718178,0.0006487337,0.0006392232,0.0000213862,0.0001315358,0.000004134427,0.001588986],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001356921,"threshold_uncertainty_score":0.004539371,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03499079100878444,"score_gpt":0.3486252767249856,"score_spread":0.3136344857162012,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}