{"id":"W4392809607","doi":"10.3390/brainsci14030276","title":"The Association among Hypothalamic Subnits, Gonadotropic and Sex Hormone Plasmas Levels in Alzheimer’s Disease","year":2024,"lang":"en","type":"article","venue":"Brain Sciences","topic":"Stress Responses and Cortisol","field":"Neuroscience","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Canadian Institutes of Health Research; National Institutes of Health; H. Lundbeck A/S; Servier; Eisai; National Institute of General Medical Sciences; Northern California Institute for Research and Education; Pfizer; Novartis Pharmaceuticals Corporation; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Meso Scale Diagnostics; F. Hoffmann-La Roche; University of Southern California; BioClinica; Bristol-Myers Squibb; Eli Lilly and Company; Biogen","keywords":"Internal medicine; Endocrinology; Luteinizing hormone; Testosterone (patch); Hormone; Neurodegeneration; Alzheimer's disease; Hippocampus; Disease; Effects of sleep deprivation on cognitive performance; Psychology; Medicine; Cognition; Biology; Physiology; Neuroscience","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002342521,0.0001707926,0.0001515821,0.0003888871,0.0001396739,0.0002519675,0.00008683403,0.0001255,0.0008267159],"category_scores_gemma":[0.0005071007,0.00008795642,0.0001654288,0.0002635962,0.0001456298,0.0001129641,0.0001596994,0.0001704494,0.00008460434],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001004293,"about_ca_system_score_gemma":0.00008579202,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001577276,"about_ca_topic_score_gemma":0.002544201,"domain_scores_codex":[0.9999188,0.00001840717,0.000008917499,0.00002017051,0.00001900199,0.00001474841],"domain_scores_gemma":[0.9997661,0.0000563493,0.00008341248,0.00002787892,0.0000257844,0.00004059245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004720454,0.00001947757,0.9902816,0.00001080352,0.00008722591,0.00007842688,0.00008983175,0.00002954234,0.003803656,0.00003250674,0.00004983453,0.005045046],"study_design_scores_gemma":[0.000001889334,0.0000389432,0.9994412,0.00000116275,0.00001190145,0.0001211559,0.00004139576,0.00004021957,0.0001777586,0.00002782508,0.00009550712,0.000001008378],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986939,0.0006547473,0.00008294833,0.00001850462,0.000006255679,0.000001489118,0.000147452,0.000002687859,0.000391993],"genre_scores_gemma":[0.9995321,0.0001412618,0.00006490247,0.000007964218,0.000006564633,0.000001300979,0.00007576372,0.000001183073,0.0001689217],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001577276,"threshold_uncertainty_score":0.003136158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05207392914581626,"score_gpt":0.2981362664646754,"score_spread":0.2460623373188591,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}