{"id":"W4392813867","doi":"10.1111/hae.14970","title":"Diagnosis and treatment of von Willebrand disease in 2024 and beyond","year":2024,"lang":"en","type":"review","venue":"Haemophilia","topic":"Platelet Disorders and Treatments","field":"Medicine","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Von Willebrand disease; Medicine; Von Willebrand factor; Desmopressin; Disease; Intensive care medicine; Genetic counseling; Pediatrics; Genetic testing; Genetic diagnosis; Prenatal diagnosis; Immunology; Pathology; Genetics; Internal medicine; Pregnancy; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003664374,0.0003807069,0.001706571,0.0002758935,0.0000194437,0.00001699425,0.00002853265,0.0001445871,0.00005469732],"category_scores_gemma":[0.00001855481,0.0002428301,0.0002148467,0.0002066627,0.00008773812,0.00003087646,0.00003842474,0.0001004411,0.00002173481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008665937,"about_ca_system_score_gemma":0.0001137103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005403424,"about_ca_topic_score_gemma":0.00002819584,"domain_scores_codex":[0.9988686,0.00002902394,0.0003546436,0.0004444598,0.0001235484,0.0001797473],"domain_scores_gemma":[0.9994027,0.00007809171,0.00007112174,0.000231714,0.00001070691,0.000205654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004046527,0.0004297194,0.003815882,0.01790656,0.0004639886,0.003312119,0.0001112239,2.347445e-8,4.349393e-8,0.0000328075,0.0007011553,0.973186],"study_design_scores_gemma":[0.001834136,0.0005194408,0.001380804,0.01923455,0.009026546,0.0001714334,0.00001412948,0.000008707454,7.908854e-7,0.0005925021,0.966938,0.0002790287],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01580692,0.9819179,3.275835e-8,0.0001720556,0.0001259471,0.001167103,0.000329132,0.00001374751,0.0004672083],"genre_scores_gemma":[0.001711684,0.9961213,0.00002018415,0.00001713232,0.00004704011,0.0002935208,0.0001782794,0.00004314194,0.001567741],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.972907,"threshold_uncertainty_score":0.9902322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03699742106838043,"score_gpt":0.3304672092489824,"score_spread":0.2934697881806019,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}