{"id":"W4392846179","doi":"10.1001/jamanetworkopen.2024.2388","title":"Genetics Visit Uptake Among Individuals Receiving Clinically Actionable Genomic Screening Results","year":2024,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Ted Rogers Centre for Heart Research; Hospital for Sick Children","funders":"Hospital for Sick Children; University of Toronto; Janssen Scientific Affairs; Regeneron Pharmaceuticals","keywords":"Biobank; Medicine; Medical genetics; Cohort; Odds ratio; Disease; Demography; Internal medicine; Genetics; Biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002041312,0.0002193025,0.0002187302,0.00005040917,0.0002528232,0.0008604968,0.0008702564,0.0003461383,0.0001209774],"category_scores_gemma":[0.0002170068,0.0002309379,0.0001218455,0.0003198281,0.00008765396,0.00002977178,0.001014665,0.0003350149,0.00007908409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008373008,"about_ca_system_score_gemma":0.0003726322,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004600146,"about_ca_topic_score_gemma":0.00008623955,"domain_scores_codex":[0.9977024,0.0001696123,0.000672015,0.0007966984,0.0002060586,0.000453184],"domain_scores_gemma":[0.9988001,0.0001264527,0.0001770066,0.0006639872,0.0001064025,0.000126063],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006272452,0.00006711084,0.07221961,0.00004923429,0.001121172,0.00003607118,0.0004866634,0.1432409,0.01118132,0.0002871735,0.5498117,0.2208718],"study_design_scores_gemma":[0.0008395776,0.000194473,0.1806229,0.0002381014,0.0000753718,0.00002027945,0.0001032867,0.003835517,0.001636773,0.0003973679,0.8116169,0.0004193973],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9517804,0.007458203,0.009028454,0.001973616,0.001799275,0.0009776067,0.0001617206,0.00009113268,0.02672962],"genre_scores_gemma":[0.9403591,0.001460394,0.04512037,0.0009534746,0.003888646,0.0001165665,0.0005353383,0.00009580972,0.007470344],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2618053,"threshold_uncertainty_score":0.9417374,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02956293663480889,"score_gpt":0.3272220006281577,"score_spread":0.2976590639933488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}